70 -7 (81) 2025 - Yodgorov N.A., Makhkamov N.Zh. - PATHOHISTOLOGICAL FEATURES OF FIBRINOID INVOLUTION IN MENISCAL AND CRUCIATE LIGAMENT TISSUES IN POST-TRAUMATIC GONARTHROSIS

PATHOHISTOLOGICAL FEATURES OF FIBRINOID INVOLUTION IN MENISCAL AND CRUCIATE LIGAMENT TISSUES IN POST-TRAUMATIC GONARTHROSIS

Yodgorov N.A. - Fergana Medical Institute of Public Health

Makhkamov N.Zh. - Andijan State Medical Institute

Resume

The pathohistological characteristics of fibrinoid involution in the menisci and cruciate ligaments of the knee joint during post-traumatic gonarthrosis were evaluated through morphological analysis. Accumulation of fibrinoid substance, dystrophic alterations in collagen fibers, and signs of chronic inflammation were identified. These morphological changes represent critical pathogenetic mechanisms contributing to joint dysfunction and the progression of arthrosis. Pathohistological assessment provides valuable data for determining the extent of tissue remodeling and predicting disease outcomes

Keywords: post-traumatic gonarthrosis, meniscus, cruciate ligament, fibrinoid involution, pathohistology, morphological changes

First page

373

Last page

377

For citation:Yodgorov N.A., Makhkamov N.Zh. - PATHOHISTOLOGICAL FEATURES OF FIBRINOID INVOLUTION IN MENISCAL AND CRUCIATE LIGAMENT TISSUES IN POST-TRAUMATIC GONARTHROSIS//New Day in Medicine 7(81)2025 373-377 https://newdayworldmedicine.com/en/new_day_medicine/7-81-2025

List of References

1. Афанасьев Ю.И., Смагина Н.Ю. Патоморфология соединительной ткани. — Москва: Медицина, 2019. — 256 с.
2. Resnick D., Niwayama G. Osteoarthritis of the knee. Radiology. 2002; 226(3): 609–622.
3. Липова Л.В. Морфология суставных хрящей при гонартрозе различного генеза. Вестник морфологии, 2021; 27(1): 54–59.
4. Кан А.Н., Пархоменко Г.Н. Современные представления о патогенезе остеоартроза. Травматология и ортопедия России, 2020; №1: 34–40.
5. Chen D., Shen J., Zhao W., Wang T., Han L. Osteoarthritis: toward a comprehensive understanding of pathological mechanism. Bone Research. 2017; 5:16044.
6. Караченцев С.А., Коваленко Е.А. Патология связочного аппарата коленного сустава: гистологическая характеристика. Современная ревматология. 2018; 12(2): 85–91.
7. Махкамов Носиржон Жўраевич. Тиз боғлам тўқималаридаги фибриноид ўзгаришларнинг морфологик хусусиятлари // Биомедицина ва амалиёт. – 2023. – №2. – Б. 60–64.

   file

   download