• Home
  • NEW DAY MEDICINE
  • 7 (81) 2025
  • 86 -7 (81) 2025 - Boymurodov R.R., Rakhimov R.R. - RESULTS OF HISTOCHEMICAL EXAMINATION OF THE ADRENAL GLAND IN EXPERIMENTAL RHEUMATOID ARTHRITIS

86 -7 (81) 2025 - Boymurodov R.R., Rakhimov R.R. - RESULTS OF HISTOCHEMICAL EXAMINATION OF THE ADRENAL GLAND IN EXPERIMENTAL RHEUMATOID ARTHRITIS

RESULTS OF HISTOCHEMICAL EXAMINATION OF THE ADRENAL GLAND IN EXPERIMENTAL RHEUMATOID ARTHRITIS

Boymurodov R.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Rakhimov R.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Van Gieson staining was effective in detecting interstitial fibrosis in adrenal tissues, and in cases of rheumatoid arthritis, the degree of fibrosis was found to be particularly high in the striated area. The study revealed that complex morphofunctional changes occurred in the structure of the adrenal gland against the background of rheumatoid arthritis. These changes were mainly associated with inflammatory, autoimmune and stress adaptation mechanisms, which were manifested by the re-formation of the zonal order in the morphology of the gland, vascular changes and changes in the cellular composition. These results serve as an important scientific basis for understanding the response of the adrenal gland to autoimmune and inflammatory diseases, as well as for the development of new pharmacotherapeutic approaches

Keywords: adrenal gland, white outbred rats, morphology, morphometry, cortical layer, medulla layer

First page

460

Last page

464

For citation:Boymurodov R.R., Rakhimov R.R. - RESULTS OF HISTOCHEMICAL EXAMINATION OF THE ADRENAL GLAND IN EXPERIMENTAL RHEUMATOID ARTHRITIS//New Day in Medicine 7(81)2025 460-464 https://newdayworldmedicine.com/en/new_day_medicine/7-81-2025

List of References

  1. Муркамилов И. Т. и др. Ревматоидный артрит и поражения почек: современный взгляд на проблему //The Scientific Heritage. – 2021. – №. 58-2. – С. 29-37.
  2. Рашидовна О.Г. Физиология желез внутренней секреции // Образование наука и инновatsiонные идеи в мире. – 2024. – Т. 39. – №. 3. – С. 171-179.
  3. Сапин М. Р. и др. Современные представления о строении и функциях надпочечников //Клиническая и экспериментальная морфология. – 2012. – №. 1. – С. 14-20.
  4. Соболева Е. М. Эпифизарно-гипофизарно-надпочечниковая регуляция у больных ювенильным ревматоидным артритом //Таврический медико-биологический вестник. – 2013. – №. 16, № 3 (1). – С. 148-153.
  5. Zakrevska M. V., Tybinka A. M. Peculiarities of microstructure of the suprarenal glands of rabbits with different types of autonomic tone //Regulatory Mechanisms in Biosystems. – 2019. – Т. 10. – №. 4. – С. 415-421.

    file

    download