• Home
  • NEW DAY MEDICINE
  • 7 (81) 2025
  • 87 -7 (81) 2025 - Tillashayxov M.N., Hakimov G.A. - LONG - TERM RESULTS AND COMPARATIVE ANALYSIS OF APPROACHES TO SURGICAL TREATMENT OF DIFFERENTIATED PAPILLARY THYROID CANCER

87 -7 (81) 2025 - Tillashayxov M.N., Hakimov G.A. - LONG - TERM RESULTS AND COMPARATIVE ANALYSIS OF APPROACHES TO SURGICAL TREATMENT OF DIFFERENTIATED PAPILLARY THYROID CANCER

LONG - TERM RESULTS AND COMPARATIVE ANALYSIS OF APPROACHES TO SURGICAL TREATMENT OF DIFFERENTIATED PAPILLARY THYROID CANCER

Tillashayxov M.N. - Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology Bukhara Branch Uzbekistan, Tashkent city branch of the Republican specialized scientific and practical center of oncology and radiology 100070, Republic of Uzbekistan

Hakimov G.A. - Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology Bukhara Branch Uzbekistan, Tashkent city branch of the Republican specialized scientific and practical center of oncology and radiology 100070, Republic of Uzbekistan

Malikov M.A. - Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology Bukhara Branch Uzbekistan, Tashkent city branch of the Republican specialized scientific and practical center of oncology and radiology 100070, Republic of Uzbekistan

Jumaniezov X.I. - Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology Bukhara Branch Uzbekistan, Tashkent city branch of the Republican specialized scientific and practical center of oncology and radiology 100070, Republic of Uzbekistan

Abduraximov O.N. - Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology Bukhara Branch Uzbekistan, Tashkent city branch of the Republican specialized scientific and practical center of oncology and radiology 100070, Republic of Uzbekistan

Resume

Differentiated thyroid carcinomas are assessed differently in terms of prognosis in European, Japanese, and American clinical guidelines, which leads to differences in approaches to their treatment. Materials and methods. The data of 152 patients with papillary thyroid carcinoma who underwent surgical treatment between 2008 and 2023 were analyzed. The average follow-up period was 15.4 years, with a maximum of 28 years. Results. The study showed a favorable prognosis for the disease, despite the lack of sonography and fine-needle biopsy during the years under consideration, which led to a later diagnosis and surgical treatment of the tumor process. The key factors affecting the prognosis were the size of the tumor at the time of surgery and the presence of distant metastases. The long-term results of treatment were almost independent of the extent of surgical intervention (total thyroidectomy or partial removal of the gland) and the performance of prophylactic lymphodissection. Mortality rates and the frequency of relapse in patients who did not receive therapy with radioactive iodine corresponded to the data presented in the literature

Keywords: papillary thyroid carcinoma, surgical treatment, long-term results

First page

465

Last page

472

For citation:Tillashayxov M.N., Hakimov G.A., Malikov M.A., Jumaniezov X.I., Abduraximov O.N. - LONG - TERM RESULTS AND COMPARATIVE ANALYSIS OF APPROACHES TO SURGICAL TREATMENT OF DIFFERENTIATED PAPILLARY THYROID CANCER//New Day in Medicine 7(81)2025 465-472 https://newdayworldmedicine.com/en/new_day_medicine/7-81-2025

List of References

  1. Watkinson JC. The British Thyroid Association guidelines for the management of thyroid cancer in adults. Nucl Med Commun. 2004 Sep;25(9):897-900.
  2. Cooper D, Doherty G, Haugen B et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2009;19:1167-1213.
  3. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology. Thyroid carcinoma. 2010;1.
  4. Thyroid Carcinoma Task Force. AACE/AAES medical/surgical guidelines for clinical practice: management of thyroid carcinoma. Endocrinol Pract. 2001;7:202-220.
  5. The Japanese Society of Thyroid Surgery/The Japanese Society of Endocrine Surgeons. Guidelines for management of thyroid tumor. Kanehara Press, Tokyo, 2010.
  6. Schlumberger M, Challeton C, De Vathaire F et al. Radioactive iodine treatment and external radiotherapy for lung and bone metastases from thyroid carcinoma. J Nucl Med. 1996;37(4):598-605.
  7. Lin JD, Huang MJ, Juang JH et al. Factors related to the survival of papillary and follicular thyroid carcinoma patients with distant metastases. Thyroid. 1999;9(12):1227-1235.
  8. Durante C, Haddy N, Baudin E et al. Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy. J Clin Endocrinol Metab. 2006;91(8):2892-2899.
  9. Das DK. Psammoma body: a product of dystrophic calcification or of a biologically active process that aims at limiting the growth and spread of tumor. Diagn Cytopathol. 2009;37(7):534-541.
  10. Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973–2002. JAMA. 2006;295(18):2179-2182.

    file

    download