7 -8 (82) 2025 - Khaidarova D.K., Sulaymоnov M.N. - PREDICTION OF PAIN SYNDROME IN POSTHERPETIC NEURALGIA BASED ON CLINICAL SYMPTOMS AND BLOOD BIOMARKERS

PREDICTION OF PAIN SYNDROME IN POSTHERPETIC NEURALGIA BASED ON CLINICAL SYMPTOMS AND BLOOD BIOMARKERS

Khaidarova D.K. - Tashkent State Medical University

Sulaymоnov M.N. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Postherpetic neuralgia (PHN) represents one of the most severe complications of herpes zoster, characterized by persistent pain syndrome that significantly reduces patients' quality of life. Traditional approaches to predicting PHN development were based predominantly on clinical risk factors such as age, severity of the acute phase, and lesion localization. However, modern studies demonstrate the necessity of an integrated approach, including analysis of biomarkers of inflammation, neurodegeneration, and pain sensitivity for more accurate prediction of disease course. The aim of the study is to develop a comprehensive prognostic model for pain syndrome development in PHN based on a combination of clinical parameters and laboratory blood biomarkers.

Keywords: postherpetic neuralgia, pain syndrome, biomarkers, prediction, inflammatory cytokines, neuropeptides, herpes zoster, chronic pain

First page

37

Last page

41

For citation:Khaidarova D.K., Sulaymоnov M.N. - PREDICTION OF PAIN SYNDROME IN POSTHERPETIC NEURALGIA BASED ON CLINICAL SYMPTOMS AND BLOOD BIOMARKERS//New Day in Medicine 8(82)2025 37-41 https://newdayworldmedicine.com/en/new_day_medicine/8-82-2025

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