53 -8 (82) 2025 - Madatov K.A., Ismailov U.S. - PROGNOSTIC ROLE OF CATIONIC TRYPSINOGEN (PRSS1) GENE POLYMORPHISMS IN VARIOUS FORMS OF ACUTE PANCREATITIS

PROGNOSTIC ROLE OF CATIONIC TRYPSINOGEN (PRSS1) GENE POLYMORPHISMS IN VARIOUS FORMS OF ACUTE PANCREATITIS

Madatov K.A. - Tashkent State Medical University

Ismailov U.S. - Tashkent State Medical University

Sharapov A.N. - Tashkent State Medical University

Matmuratov S.K. - Tashkent State Medical University

Resume

This article examines the impact of the Arg122His polymorphism in the PRSS1 gene on the incidence of acute pancreatitis. In the mechanism of acute pancreatitis development, environmental factors play an important role alongside genetic factors. Ethnic differences in the frequency distribution of alleles and genotypes of this gene's polymorphic variant were identified. Further advancement of molecular genetic research through studying the genetic basis of pancreatitis is crucial for developing new diagnostic methods and determining treatment strategies with an individualized approach to each patient.

Keywords: cationic trypsinogen (PRSS1), gene polymorphism.

First page

298

Last page

302

For citation:Madatov K.A., Ismailov U.S., Sharapov A.N., Matmuratov S.K. - PROGNOSTIC ROLE OF CATIONIC TRYPSINOGEN (PRSS1) GENE POLYMORPHISMS IN VARIOUS FORMS OF ACUTE PANCREATITIS//New Day in Medicine 8(82)2025 298-302 https://newdayworldmedicine.com/en/new_day_medicine/8-82-2025

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