48 -9 (83) 2025 - Nazirov P.Kh., Rustamov F.Kh. - SPECIFIC FEATURES OF THE CLINICAL COURSE OF TUBERCULOUS COXITIS IN THE POPULATION OF THE PRE-ARAL ZONE

SPECIFIC FEATURES OF THE CLINICAL COURSE OF TUBERCULOUS COXITIS IN THE POPULATION OF THE PRE-ARAL ZONE

Nazirov P.Kh. - Republican Specialized Scientific and Practical Medical Center of Phthisiology and Pulmonology, Ministry of Health of the Republic of Uzbekistan

Rustamov F.Kh. - Republican Specialized Scientific and Practical Medical Center of Phthisiology and Pulmonology, Ministry of Health of the Republic of Uzbekistan

Seitbaev I.Sh. - Republican Specialized Scientific and Practical Medical Center of Phthisiology and Pulmonology, Ministry of Health of the Republic of Uzbekistan, Medical Institute of Karakalpakstan

Resume

Tuberculous coxitis is one of the most severe forms of osteoarticular tuberculosis, characterized by a prolonged chronic course, pronounced morphological changes in the hip joint, and a high rate of disability among patients. In the Aral Sea region, where adverse environmental conditions persist, including high levels of dust and toxic-chemical exposure as well as reduced overall resistance of the population, there has been an increase in the incidence of extrapulmonary forms of tuberculosis, including lesions of the osteoarticular system. In patients living in the Aral Sea area, tuberculous coxitis is more often manifested by: a protracted latent onset with nonspecific symptoms; delayed diagnosis due to its resemblance to nonspecific arthritis; severe pain syndrome and restricted hip joint mobility; rapid progression of destructive processes in bone and joint tissues; and a high frequency of drug resistance of the pathogen to first-line anti-tuberculosis drugs. The clinical course of the disease in the Aral Sea region is aggravated by social factors such as low living standards, limited access to specialized medical care, and delayed initiation of chemotherapy. All these factors contribute to the development of complicated forms of coxitis, accompanied by deformities, limb shortening, ankylosis, and persistent loss of working capacity.

Keywords: tuberculous coxitis, isoniazid, rifampicin, anti-tuberculosis therapy, ethambutol, resistance, anti-tuberculosis drugs

First page

296

Last page

300

For citation:Nazirov P.Kh., Rustamov F.Kh., Seitbaev I.Sh. - SPECIFIC FEATURES OF THE CLINICAL COURSE OF TUBERCULOUS COXITIS IN THE POPULATION OF THE PRE-ARAL ZONE//New Day in Medicine 9(83)2025 296-300 https://newdayworldmedicine.com/en/new_day_medicine/9-83-2025

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