26 -2 (40) 2022 — Z.A. Nuruzova, F.Sh. Mamatmusayeva, — DETERMINATION OF HELICOBACTER PYLORI STRAMES FOR ANTIBIOTICS AND INCREASING EFFECTIVENESS OF TREATMENT

DETERMINATION OF HELICOBACTER PYLORI STRAMES FOR ANTIBIOTICS AND INCREASING EFFECTIVENESS OF TREATMENT

Z.A. Nuruzova, Tashkent Mrdical Academiy

F.Sh. Mamatmusayeva, Tashkent Mrdical Academiy

M.A. Abdusoatova Tashkent Mrdical Academiy

Resume

The purpose of the study. Detection of Helicobacter pylori in patients with suspected gastric cancer. Materials and methods: RIO and RIATIM (Republican Specialized Scientific-Practical Research Center of Oncology and Radiology) examined the blood serum and gastric contents of 85 patients aged 30-70 years with gastric cancer and MALT lymphoma. Analysis and discussion of results. Forty-one patients with gastric cancer and 44 patients with gastric MALT lymphoma were selected for screening. The main group was 27 (65.8%) patients with gastric cancer. The diagnosis of gastric cancer in these patients was confirmed by endoscopic examination and IFA serological examination was performed to determine the concentration of H. pylori. When it was confirmed that the concentration of this bacterium was high in them, such patients were involved in bacteriological examination. Conclusion. According to the results of our study on antibiotic resistance, it is necessary to identify H. pylori and perform an antibioticogram. During our examinations, it was found that based on the results of bacteriological examinations, the drugs of choice in treatment are levofloxacin, amoxacillin, tetrocycline, chlorithromycin.

Key words: gastric cancer, Helicobacter pylori, MALT lymphoma, antibiotics

First page

135

Last page

139

For citation: Z.A. Nuruzova, F.Sh. Mamatmusayeva, M.A. Abdusoatova DETERMINATION OF HELICOBACTER PYLORI STRAMES FOR ANTIBIOTICS AND INCREASING EFFECTIVENESS OF TREATMENT //New Day in Medicine 2(40)2022 135-139 https://cutt.ly/qAkzM2K

LIST OF REFERENCES:

1. O.K. Rozdeev, A.O. Pozdeeva Yu.V. Valeeva P.E. Gulyaev 3,A., N. Savinova // Me’da shilliq qavatining epiteliyasi bilan helikobakter plyorining o’zaro ta’sir mexanikasi. Tomonidan.2018-yil. 2, 253-261 betlar.
2. I.V. Maev Klinik ahamiyatga ega) HELICOBACTER PYLORI INFEKTSION HAQIDA // Klinik tibbiyot, N 8, 2013, 4-12 st).
3. Hoi JKY, Lai WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D, Mafertheiner P, Graham) DY, Wong VWS, Wu JCY, Chan FKL, Sung JJY, Kaplan G.G., Ng S.C. Helicobacter pylori infektsiyasining global tarqalishi: tizimli tekshirish va meta-tahlil. Gastroenterologiya.2017; 153: 420-9. Doi: 10.1053 / j. gastro.2017.04.022. 
4. Bordin D.S., Embutnieks Yu.V., Vologzhanina L.G. va boshqalar). Helicobacter pylori Evropa reestri (Hp -Eureg): Rossiyada birinchi darajali terapiya olgan 2360 bemor ma’lumotlarining tahlili. Terapevtik arxiv 2018; 90 (2): 35-42 [Vordin D.S., Embutnieks Y.V., Vologzhanina L.G., va boshqalar. al. Helicobacter pylori infektsiyasini boshqarish bo’yicha Evropa reestri (Nr-EuReg): Rossiyada birinchi darajali davolanayotgan 2360 bemorning tahlili. Terapevtik arxiv. 2018; 90 (2): 35-42 (Rus tilida).] doi : 10.26442 / terarkh201890235-42.
5. Zucca E. ESMO diagnostikasi, davolash va davolash bo’yicha klinik ko’rsatmalar.oshqozon MALT limfomasini kuzatish.  Tibbiy onkologiya bo’yicha Evropa jamiyatining minimal klinik ko’rsatmalari (ESMO).  Moskva.  2017. S. 276-278.
6. Gisbert J.P., Aguado B., Luna M. va boshqalar. Gastrik MALT limfoma: H. pylori infektsiyasining klinik xususiyatlari va tarqalishi). 37 holatlar ketma-ketligida. Rev Esp Enferm Dig. 2016. Sent. 98 (9). S. 655-65.
7. Kostalanova Yu.V., Koroleva I.A., Kostalanova Yu.V., Koroleva I.A., Davydkin I.L., Osadchuk A.M. i soavt. MALT-limfoma geludka: sovremennoia sostoianiae rroblemi. Effektivnaia farmakoterapiya. Onkologiya, gematologiya va radiologiya. 2013. N ° 4.S. 26-29.