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  • 37 -10 (84) 2025 - Axmedov K.X., Alimova N.M. - CHARACTERIZATION OF LIVER ANTIOXIDANT DEFENSE SYSTEMS IN THE DYNAMICS OF EXTRAHEPATIC CHOLESTASIS

37 -10 (84) 2025 - Axmedov K.X., Alimova N.M. - CHARACTERIZATION OF LIVER ANTIOXIDANT DEFENSE SYSTEMS IN THE DYNAMICS OF EXTRAHEPATIC CHOLESTASIS

CHARACTERIZATION OF LIVER ANTIOXIDANT DEFENSE SYSTEMS IN THE DYNAMICS OF EXTRAHEPATIC CHOLESTASIS

Axmedov K.X. - Termez Branch of Tashkent State Medical University

Alimova N.M. - Termez Branch of Tashkent State Medical University

Uroqova Sh.A. - Termez Branch of Tashkent State Medical University

Resume

In experimental extrahepatic cholestasis, the activity of the liver’s antioxidant defense systems was evaluated. Extrahepatic cholestasis is accompanied by a decrease in SOD activity and a compensatory increase in catalase activity, which at early stages reflects an adaptive response to enhanced lipid peroxidation, while prolonged obstruction leads to depletion of the antioxidant defense and progressive liver tissue damage.

Keywords: experiment, cholestasis, liver, SOD, KAT.

First page

198

Last page

202

For citation:Axmedov K.X., Alimova N.M., Uroqova Sh.A. - CHARACTERIZATION OF LIVER ANTIOXIDANT DEFENSE SYSTEMS IN THE DYNAMICS OF EXTRAHEPATIC CHOLESTASIS//New Day in Medicine 10(84)2025 198-202 https://newdayworldmedicine.com/en/new_day_medicine/10-84-2025

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