39 -2 (40) 2022 — Akhmedova M.D., Sultonova G.Yu., — INTESTINAL DYSBACTERIOSIS IN PATIENTS WITH VIRAL ETIOLOGICAL LIVER CIRRHOSIS

INTESTINAL DYSBACTERIOSIS IN PATIENTS WITH VIRAL ETIOLOGICAL LIVER CIRRHOSIS

Akhmedova M.D., Tashkent Medical Academy, Tashkent, Uzbekistan

Sultonova G.Yu., Tashkent Medical Academy, Tashkent, Uzbekistan

Mirzajonova D.B. Republican Specialized Scientific-Practical Medical Center for Epidemiology, Microbiology, Infectious and Parasitic Diseases, Tashkent,

Resume

Purpose: to study the state of the intestinal microflora in patients with liver cirrhosis of viral etiology and pathogenetic justify therapeutic measures, taking into account the severity of the course of the disease, the period of therapy. During the clinical examination, intestinal dysbiosis was found in 68 (75.5%) patients. It was manifested by flatulence (p=0.01), swelling, stool instability, aching pains in the umbilical region and lower abdomen. The frequency of detection of disorders of the intestinal microflora depended on the stage of cirrhosis compensation. Intestinal dysbiosis was detected with a frequency in class B and C cirrhosis was 35 (51.4%) and 21 (30.8%), and in 12 (17.6%) in class A cirrhosis. In our studies, intestinal dysbiosis was identified with HBV cirrhosis in 11 (12.2%), HCV cirrhosis in 6 (6.6%), HBV+HCV cirrhosis in 6 (6.6%), HBV + HDV cirrhosis in 39 (43.3 %), HBV+ HDV+HCV-LC in 6 (6.6%) out of 90 observed patients with cirrhosis of viral etiology.

Keywords: liver cirrhosis, intestinal microflora, probiotic.             

 First page

207

Last page

212

For citation: Akhmedova M.D., Sultonova G.Yu., Mirzajonova D.B. INTESTINAL DYSBACTERIOSIS IN PATIENTS WITH VIRAL ETIOLOGICAL LIVER CIRRHOSIS //New Day in Medicine 2(40)2022 207-212 https://cutt.ly/wATJJc7

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