108 -10 (84) 2025 - Abbasov D.I. - MORPHOLOGICAL EFFECTS OF HIGHLY MINERALIZED GROUNDWATER ON THE STRUCTURE OF TESTES AND EPIDIDYMIS IN MALE RATS

MORPHOLOGICAL EFFECTS OF HIGHLY MINERALIZED GROUNDWATER ON THE STRUCTURE OF TESTES AND EPIDIDYMIS IN MALE RATS

Abbasov D.I. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This study investigates the morphological effects of highly mineralized groundwater on the structure of the testes and epididymis in male rats. A total of 180 white non-pedigreed male rats were used in the experiment. They were divided into control and experimental groups and were supplied with water of varying mineralization levels for 6 and 9 months. The obtained results revealed that long-term consumption of mineralized groundwater caused degenerative changes in the tissues of the testes and epididymis. In particular, a decrease in the height of the seminiferous epithelial cells, accumulation of protein and lipid granules in the cytoplasm, thickening of vascular walls, and an increase in connective tissue elements in the interstitial area were observed. Additionally, leukocyte infiltration, narrowing of the tubular lumen, and thickening of the epithelial layer were recorded. In contrast, the control group animals showed normal histological structures of the testes and epididymis. These findings confirm that high concentrations of sulfates, chlorides, and nitrates in the water have a detrimental effect on the cellular structure of reproductive organs. The results highlight the importance of hygienic monitoring of drinking water mineralization levels and demonstrate that maintaining the chemical balance of water is crucial for preserving the normal morphological condition of male reproductive glands.

Keywords: groundwater, mineralization, testes, epididymis, morphology, histology, reproductive system, rats.

First page

619

Last page

624

For citation:Abbasov D.I. - MORPHOLOGICAL EFFECTS OF HIGHLY MINERALIZED GROUNDWATER ON THE STRUCTURE OF TESTES AND EPIDIDYMIS IN MALE RATS//New Day in Medicine 10(84)2025 619-624 https://newdayworldmedicine.com/en/new_day_medicine/10-84-2025

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