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  • 29 -11 (85) 2025 - Kadirova Z.S., Khalimova Z.Yu. - INFLUENCE OF VITAMIN D DEFICIENCY ON THE DEVELOPMENT OF IMMUNOPATHOLOGY OF AUTOIMMUNE THYROIDITIS

29 -11 (85) 2025 - Kadirova Z.S., Khalimova Z.Yu. - INFLUENCE OF VITAMIN D DEFICIENCY ON THE DEVELOPMENT OF IMMUNOPATHOLOGY OF AUTOIMMUNE THYROIDITIS

INFLUENCE OF VITAMIN D DEFICIENCY ON THE DEVELOPMENT OF IMMUNOPATHOLOGY OF AUTOIMMUNE THYROIDITIS

Kadirova Z.S. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Khalimova Z.Yu. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Autoimmune thyroiditis (AIT) is one of the most common autoimmune diseases affecting the thyroid gland with thyroid-specific autoantibodies, characterized by lymphocytic infiltration and the development of hypothyroidism. Although the exact etiology is not fully understood, AIT is associated with the interaction of genetic elements, environmental factors, and epigenetic influences. Vitamin D, which is an important micronutrient in our body, besides participating in the metabolism of calcium and phosphorus, performs an immunomodulatory function and, apparently, promotes immune tolerance. The purpose of this study is to conduct a review analysis of the relationship between vitamin D levels and AIT. There is extensive literature confirming that patients with AIT have significantly lower vitamin D levels than healthy people. The principle of action underlying this phenomenon is still unknown, so it is necessary to clarify the role and mechanism of action of vitamin D in the occurrence and development of AIT. This knowledge will help develop intervention and early treatment strategies for patients with AIT who have low vitamin D levels.

Key words: autoimmune thyroiditis, interleukins, vitamin D, thyroglobulin antibodies, thyroid peroxidase antibodies, autoimmunity, immune cells.

First page

156

Last page

162

For citation:Kadirova Z.S., Khalimova Z.Yu. - INFLUENCE OF VITAMIN D DEFICIENCY ON THE DEVELOPMENT OF IMMUNOPATHOLOGY OF AUTOIMMUNE THYROIDITISN//New Day in Medicine 11(85)2025 156-162 https://newdayworldmedicine.com/en/new_day_medicine/11-85-2025

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