52 -2 (40) 2022 — Akhmedova M.D., Niyazova T.A., — MOLECULAR STUDY OF LONG-TERM CELL PARASITISM OF BRUCELL

MOLECULAR STUDY OF LONG-TERM CELL PARASITISM OF BRUCELL

Akhmedova M.D., Tashkent Medical Academy,  Uzbekistan

Niyazova T.A., Tashkent Medical Academy,  Uzbekistan

Anvarov J.A., Tashkent Medical Academy,  Uzbekistan

 Zaylobidinov B.Z. Tashkent Medical Academy,  Uzbekistan

Resume

Specific evolution in relation to the macroorganism allows brucella to remain stable inside the cell, long-term persistence in immune cells by regulating the cellular immunity of the macroorganism. The evolution of Brucella is aimed at intracellular storage and is mainly due to resistance to cellular lysosomal enzymes. The article shows the molecular mechanisms that provide intracellular persistence of the brucellosis pathogen. Understanding the molecular mechanisms of intracellular storage of bacteria will greatly help us to increase epidemiological control over brucella bacteria and to develop new methods and means of prevention and treatment.

Keywords: Brucellosis, Brucella, macroorganism, intracellular parasitism, immunity, cytokines, genes.

First page

278

Last page

282

For citation: Akhmedova M.D., Niyazova T.A., Anvarov J.A., Zaylobidinov B.Z. MOLECULAR STUDY OF LONG-TERM CELL PARASITISM OF BRUCELL //New Day in Medicine 2(40)2022 278-282 https://cutt.ly/uAFpKEh

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