91 -11 (85) 2025 - Usmonova Z.Y., Karimova G.K. - EARLY PREDICTION OF PRETERM BIRTH RISK IN WOMEN WITH BACTERIAL VAGINOSIS -

EARLY PREDICTION OF PRETERM BIRTH RISK IN WOMEN WITH BACTERIAL VAGINOSIS

Usmonova Z.Y. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Karimova G.K. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This study investigated the possibilities for early prediction of preterm birth risk in pregnant women diagnosed with bacterial vaginosis (BV). The research included 21 retrospective, 34 prospective, and 15 healthy control pregnant women. Clinical and laboratory parameters, vaginal microflora composition, and biomarkers associated with preterm delivery were analyzed. The findings demonstrated that bacterial vaginosis significantly increases the risk of preterm birth, and that early diagnosis and preventive interventions can effectively reduce this risk.

Keywords: bacterial vaginosis, preterm birth, vaginal microflora, biomarkers, pregnancy risk.

First page

537

Last page

540

For citation:Usmonova Z.Y., Karimova G.K. - EARLY PREDICTION OF PRETERM BIRTH RISK IN WOMEN WITH BACTERIAL VAGINOSIS//New Day in Medicine 11(85)2025 537-540 https://newdayworldmedicine.com/en/new_day_medicine/11-85-2025

List of References

  1. Romero R. et al. Microbial invasion of the amniotic cavity and preterm birth. // Am J Obstet Gynecol. 2015.
  2. Nugent R. P. et al. Diagnostic criteria for bacterial vaginosis. // Am J Obstet Gynecol. 1991.
  3. Leitich H. et al. Bacterial vaginosis as a risk factor for preterm delivery. // Obstet Gynecol. 2003.
  4. WHO Report, 2023: Preterm Birth Statistics.
  5. O‘zbekiston Sog‘liqni Saqlash Vazirligi, Perinatal tibbiyot bo‘yicha klinik qo‘llanma, 2024.
  6. Qayumova, G.M. ҳаммуаллиф. "Muddatdan oldin qog’onoq suvining ketishida xavf omillarning ta’sirini baholash." // Журнал гуманитарных и естественных наук, 2023;2(7):11-18.
  7. Raju T.N.K. "Outcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes." // Eunice Kennedy Shriver National Institute of Child Health and Human Development, 22 Apr. 2021.
  8. Raveena Shree.J. "Fetomaternal Outcome in Preterm Premature Rupture of Membranes: A Retrospective Study." Journal of Neonatal Surgery, 2025.
  9. Sananès, N. et al. "Prediction of spontaneous preterm delivery in singleton pregnancies: where are we and where are we going? A review of literature." J Obstet Gynaecol., 2014 Aug; 34(6):457-61.
  10. Skupski, Daniel W. "Preterm prelabor rupture of membranes: A focus on antenatal corticosteroids and latency." Seminars in Perinatology, 2022;46(1):151528.
  11. Sola-Viso, R. "Novel biomarkers in the management of preterm premature rupture of membranes: A systematic review." European Journal of Obstetrics & Gynecology and Reproductive Biology, 2020;248:208-216.
  12. Tincello D. G. "Preterm prelabour rupture of the membranes (PPROM): a study of patient experiences and support needs." Taylor & Francis Online, 2024.
  13. Tosheva, I.I. and et all. "Labor outcomes in pregnant women with premature rupture of amniotic fluid." Bulletin of the Dagestan State Medical Academy, 2019;4(33):34-38.
  14. Tosheva I.I. and et all. "The role of premature rupture of amniotic fluid on the development of obstetric complications." Collection of scientific papers based on the materials of the International scientific conference dedicated to the 85th anniversary of Kursk State Medical University, 2020;1:601-605.
  15. Tosheva I.I.and et all. "Morphological and microbiological changes in the placenta in women with premature rupture of amniotic fluid." // Journal of Problems of Biology and Medicine, 2019;4.2(115):146-149.
  16. Vounzoulaki Eleni. "Risk prediction models for preterm birth: a systematic review and meta-analysis." // British Journal of Obstetrics and Gynaecology, 2022;129(5):685-697.

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