30 -12 (86) 2025 - Obidov I.U. - MULTI-FACTOR ETIOPATHOGENESIS OF GASTRIC AND DUODENAL PEPTIC ULCER DISEASE

MULTI-FACTOR ETIOPATHOGENESIS OF GASTRIC AND DUODENAL PEPTIC ULCER DISEASE

Obidov I.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Gastric and duodenal peptic ulcer disease is a multifactorial pathology, in the etiopathogenesis ofwhich the general and local reactions of the body to external and internal risk factors play a role. Psychoemotional stress is the main cause of the pathology of nervous and humoral regulation (general reaction), and the local reaction is expressed in a violation of the ratio between the factors of aggression and protection factors in the mucous membrane of the stomach and / or duodenum. The combined action of these components leads to the formation of an ulcerative defect.

Key words: peptic ulcer disease, factors of aggression and protection factors, acid-peptic factor, Helicobacter pylori, heredity, stress

First page

173

Last page

178

For citation:Obidov I.U. - MULTI-FACTOR ETIOPATHOGENESIS OF GASTRIC AND DUODENAL PEPTIC ULCER DISEASE//New Day in Medicine 12(86)2025 173-178 https://newdayworldmedicine.com/en/new_day_medicine/12-86-2025

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