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  • 72 -9 (59) 2023 - Abdulloev M.Z., Oblokulov A.R. - ANALYSIS OF THE RESULTS OF THE STUDY ON THE DETERMINATION OF CYTOKINES IN PATIENTS WITH CHRONIC HEPATITIS C DEPENDING ON THE PRESENCE OF CRIGLOBULINEMIA

72 -9 (59) 2023 - Abdulloev M.Z., Oblokulov A.R. - ANALYSIS OF THE RESULTS OF THE STUDY ON THE DETERMINATION OF CYTOKINES IN PATIENTS WITH CHRONIC HEPATITIS C DEPENDING ON THE PRESENCE OF CRIGLOBULINEMIA

ANALYSIS OF THE RESULTS OF THE STUDY ON THE DETERMINATION OF CYTOKINES IN PATIENTS WITH CHRONIC HEPATITIS C DEPENDING ON THE PRESENCE OF CRIGLOBULINEMIA

Abdulloev M.Z. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Oblokulov A.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

40 patients with CHC with extrahepatic manifestations were involved in the conducted studies to determine the cytokines IL-10 and IL-18 in patients with CHC, depending on the presence of cryglobulinemia. The results of the study showed that in patients with chronic hepatitis C with extrahepatic manifestations, the anti-inflammatory cytokine IL-10 was reduced by 2.37 times in patients, and there was a significant increase in the content of pro-inflammatory cytokine IL-18 in the blood serum by 2.71 times in relation to normal values.

Key words: chronic hepatitis C, extrahepatic manifestations, cryoglobulin, interleukin, cytokine., procalcitonin

First page

399

Last page

405

For citation: Abdulloev M.Z., Oblokulov A.R. – ANALYSIS OF THE RESULTS OF THE STUDY ON THE DETERMINATION OF CYTOKINES IN PATIENTS WITH CHRONIC HEPATITIS C DEPENDING ON THE PRESENCE OF CRIGLOBULINEMIA//New Day in Medicine 2023 9(59): 399-405 https://newdaymedicine.com/index.php/2023/10/18/l-465/

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