76 -12 (86) 2025 - Safoyev B.B., Kuramysov E.A., Khamroev Sh.M. - A NEW METHOD OF WOUND TREATMENT IN DIABETIC FOOT SYNDROME

A NEW METHOD OF WOUND TREATMENT IN DIABETIC FOOT SYNDROME

Safoyev B.B. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Kuramysov E.A. - Kazakh National Medical University named after S.D. Asfendiyarov

Khamroev Sh.M. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Objective. Improving the results of treatment of patients with diabetic foot syndrome with critical lower limb ischemia through the use of an improved ultrasound wound treatment method. Materials and methods. The work is based on the examination and treatment data of 123 patients with critical lower limb ischemia with severe diabetic foot syndrome complicated by purulent wounds who received inpatient treatment at the clinical base of the Bukhara State Medical Institute from 2024 to 2025. Results. In severe diabetic foot syndrome with critical lower limb ischemia, the use of well-known methods of modern endovascular interventions and local wound treatment against the background of diabetic foot syndrome using ultrasonic wound treatment a 25% dimexide solution and an electroactivated solution – And in diabetic foot syndrome, it is a more effective way than using ultrasound treatment of a wound with saline solution or using a 25% dimexide solution, which is manifested in accelerating healing processes and improving intoxication rates by an average of 2-4 days, eliminating cases of high amputation, reducing the number of amputations at the shin level from 18.9% to 7.5%, atypical foot resection from 24.3% to 15.0%, reamputation from 5.4% to zero, suppuration of the postoperative stump from 5.4% to 2.5% of cases compared with the II A subgroup. Conclusions. Due to a decrease in the number of highly traumatic operations, there was an increase in the following low-traumatic operations, such as finger amputation from 32.4% to 47.5%, necrectomy from 21.6% to 30.0%, respectively. Mortality in the application of ultrasound wound treatment with a 25% dimexide solution and electroactivated solution - A was not noted, unlike in previous comparison groups. The average length of bed days was 7.1±0.8 days.

Keywords: diabetic foot syndrome, critical lower limb ischemia, ultrasound wound treatment, dimexide solution, electroactivated solution

First page

420

Last page

428

For citation:Safoyev B.B., Kuramysov E.A., Khamroev Sh.M. - A NEW METHOD OF WOUND TREATMENT IN DIABETIC FOOT SYNDROME //New Day in Medicine 12(86)2025 420-428 https://newdayworldmedicine.com/en/new_day_medicine/12-86-2025

List of References

  1. Есипов А.В., Алехнович А.В., Мусаилов В.А., Маркевич П.С., Потапов В.А. Актуальные проблемы диагностики синдрома диабетической стопы. Вестник Национального медико-хирургического Центра им. Н.И. Пирогова 2023, т. 18, №2 115-120 / Esipov A.V., Alexnovich A.V., Musailov V.A., Markevich P.S., Potapov V.A. Current problems in the diagnosis of diabetic foot syndrome. Vestnik Natsionalnogo mediko-xirurgicheskogo Sentra im. N.I. Pirogova 2023;18(2):115-120. (In Russ.)
  2. Галстян Г.Р., Токмакова А.Ю., Бондаренко О.Н., Ситкин И.И., Пряхина К.Ю., Митиш В.А., Доронина Л.П. Заболевания артерий нижних конечностей у пациентов с сахарным диабетом: состояние проблемы и перспективы лечения. Сахарный диабет. 2011;14(1):74-80. https://doi.org/10.14341/2072-0351-6253 / Galstyan G.R., Tokmakova A.Yu., Bondarenko O.N., Sitkin I.I., Pryaxina K.Yu., Mitish V.A., Doronina L.P. Diseases of the arteries of the lower extremities in patients with diabetes mellitus: the state of the problem and treatment prospects. Saxarniy diabet. 2011;14(1):74-80. (In Russ.)
  3. Safoev B.B., Nazarov J.R., Boltaev T.Sh. Differential approach of endovascular intervention in the treatment of patients with critical lower limb ischemia with diabetes. 中华劳动卫生职业病杂志2022年13月第40卷第13期Chin J Ind Hyg Occup Dis, 2022. P.838 – 844.
  4. Boltaev T.Sh. Effectiveness of endovascular treatment for obliterating atherosclerosis on the background of diabetes mellitus. AMERICAN Journal of Pediatric Medicine and Health Sciences 2023;1(9). ISSN (E): 2993-2149 https://grnjournal.us/ index.php /AJPMHS/article/view/ 1252/1064.
  5. Яровенко А.М., Ступак В.С., Люцко В.В., Кораблев В.Н., Димова О.А. Ампутации нижних конечностей при синдроме диабетической стопы: вопросы организации раннего выявления и профилактики осложнений. Научно-практический рецензируемый журнал "Современные проблемы здравоохранения и медицинской статистики" 2024 г., №1, 1115-1134. / Yarovenko A.M., Stupak V.S., Lyusko V.V., Korablev V.N., Dimova O.A. Amputations of the lower extremities in diabetic foot syndrome: issues of early detection and prevention of complications. Scientific journal "Current problems of health care and medical statistics" 2024 г., № 1, 1115-1134. (In Russ.)
  6. Казиев У. К., Мусаев У.С., Иманкулова А.С., Миклухин Д.С. Опыт применения ультразвуковой кавитации в лечении ран у пациентов с гнойно-некротическими осложнениями синдрома диабетической стопы. Раны и раневые инфекции журнал им. проф. Б.М. Костючёнка 2024; 11 (2): 30-36 DOI: 10.25199/2408-9613-2024-11-2-28-34. / Kaziev U. K., Musaev U.S., Imankulova A.S., Mikluxin D.S. Experience of ultrasonic cavitation in the treatment of wounds in patients with purulent-necrotic complications of diabetic foot syndrome Rany i ranevyye infektsii. Zhurnal im. prof. B. M. Kostyuchonka. 2024;11(2):30-36 (In Russ.)
  7. Митиш В. А., Пасхалова Ю. С., Муньос Сэпэда П.А. Ультразвуковая кавитация в лечении нейроишемической формы синдрома диабетической стопы при наличии биопленочных форм бактерий (обзор литературы). Раны и раневые инфекции. Журнал им. проф. Б. М. Костючёнка. 2020;7(3):20–31. / Mitish V. A., Paskhalova Yu. S., Munioz Sepeda P. A., et al. Ultrasonic cavitation in the treatment of neuro-ischemic diabetic foot the presence of biofilm forms of bacteria (literature review) = Mitish V. A., Paskhalova Yu. S., Mun’os Sepeda P. A. i dr. Ul’trazvukovaya kavitatsiya v lechenii neyroishemicheskoy formy sindroma diabeticheskoy stopy pri nalichii bioplenochnykh form bakteriy (obzor literatury). Rany i ranevyye infektsii. Zhurnal im. prof. B. M. Kostyuchonka. 2020;7(3):20–31. (In Russ).
  8. Гурьева И.В. Возможности местного лечения диабетических поражений стоп. Русский медицинский журнал. 2002;10(11):509–512. / Guryeva I. V. Possibilities of local treatment of diabetic foot lesions = Gur’yeva I. V. Vozmozhnosti mestnogo lecheniya diabeticheskikh porazheniy stop. Russkiy meditsinskiy zhurnal. 2002;10(11):509–512. (In Russ.)
  9. Привольнев В. В., Каракулина Е. В. Основные принципы местного лечения ран и раневой инфекции. Клиническая микробиология и антимикробная химиотерапия. 2011;13(3):214–222. / Privolnev V. V., Karakulina E. V. Basic principles of local treatment of wounds and wound infection = Privol’nev V. V., Karakulina E. V. Osnovnyye printsipy mestnogo lecheniya ran i ranevoy infektsiyey. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya. 2011;13(3):214–222. (In Russ.)
  10. Липатов К. В., Сопромадзе М. А., Емельянов А. Ю., Канорский И. Д. Использование физических методов в лечении гнойных ран (обзор литературы). Хирургия. 2001;10:56–61. / Lipatov K. V., Sopromadze M. A., Emelyanov A. Yu., Kanorskiy I. D. Use of physical methods in the treatment of purulent wounds (literature review) = Lipatov K. V., Sopromadze M. A., Yemel’yanov A. Yu., Kanorskiy I. D. Ispol’zovaniye fizicheskikh metodov v lechenii gnoynykh ran (obzor literatury). Khirurgiya. 2001;10:56–61. (In Russ.)

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