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  • 85 -12 (86) 2026 - Khafizova D.B., Yarashеva Sh.U. - THE IMPACT OF PRECANCEROUS CERVICAL DISEASES ON THE OUTCOMES OF IVF PROGRAMS IN WOMEN WITH THROMBOPHILIA

85 -12 (86) 2026 - Khafizova D.B., Yarashеva Sh.U. - THE IMPACT OF PRECANCEROUS CERVICAL DISEASES ON THE OUTCOMES OF IVF PROGRAMS IN WOMEN WITH THROMBOPHILIA

THE IMPACT OF PRECANCEROUS CERVICAL DISEASES ON THE OUTCOMES OF IVF PROGRAMS IN WOMEN WITH THROMBOPHILIA

Khafizova D.B. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Yarashеva Sh.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Nosirova M. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The article presents the results of colposcopic, cytological, and molecular-genetic studies of the G/A polymorphism of the F7 gene in 90 women with thrombophilia and unsuccessful IVF outcomes.The study results showed that the A allele, heterozygous G/A, and homozygous non-functional A/A genotypes of the F7 polymorphism are among the markers of an increased risk of developing thrombophilia in women of the Uzbek population.In contrast, the functional G allele and functionally favorable G/G genotype are considered functional genotypes in relation to the development of pathology (χ² = 15.48; p < 0.0004; OR = 0.03; 95% CI 0.00–0.46).

Keywords: CIN 1, colposcopy, HPV, thrombophilia, genetics, G/A polymorphism of the F7 gene.

First page

461

Last page

467

For citation:Khafizova D.B., Yarashеva Sh.U., Nosirova M. - THE IMPACT OF PRECANCEROUS CERVICAL DISEASES ON THE OUTCOMES OF IVF PROGRAMS IN WOMEN WITH THROMBOPHILIA//New Day in Medicine 12(86)2025 461-467 https://newdayworldmedicine.com/en/new_day_medicine/12-86-2025

List of References

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