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  • 73 -2 (40) 2022 — Ashurova N.G., Ismatova M.N. — MENSTRUAL DISORDERS IN ADOLESCENT GIRLS WITH INSULIN RESISTANCE

73 -2 (40) 2022 — Ashurova N.G., Ismatova M.N. — MENSTRUAL DISORDERS IN ADOLESCENT GIRLS WITH INSULIN RESISTANCE

MENSTRUAL DISORDERS IN ADOLESCENT GIRLS WITH INSULIN RESISTANCE

Ashurova N.G., Bukhara State Medical Institute, Bukhoro, Uzbekistan

Ismatova M.N. Bukhara State Medical Institute, Bukhoro, Uzbekistan

Resume

The present study applying a comprehensive diagnostic approach has revealed the specific features of clinical, hormonal, and metabolic disorders in adolescent girls in the presence of menstrual dysfunction concurrent with insulin resistance, which could identify different pathogenetic mechanisms of the above disorders. It was found that in female obese adolescents, menstrual dysfunction might be caused by compensatory hy- perinsulinemia and insulin resistance in the presence of visceral obesity. The manifestations of mixed hyperandrogenism caused by impaired steroidogenesis associated with increased p450c 17a activity come to the forefront in the group of patients with normal weight and insulin resistance.

Key words: insulin resistance, polycystic ovary syndrome, hyperandrogenism.

First page

378

Last page

382

For citation: Ashurova N.G., Ismatova M.N. MENSTRUAL DISORDERS IN ADOLESCENT GIRLS WITH INSULIN RESISTANCE //New Day in Medicine 2(40)2022 378-382 https://cutt.ly/sSGZcRj

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