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  • 152 -12 (86) 2025 - Boltaboev T.T., Eshbaev E.A. - PATHOMORPHOLOGY IMMUNOHISTOCHEMICAL ASPECTS OF REGIONAL LYMPH NODES IN DEVELOPED PERITONITIS IN CHILDREN UNDER ONE YEAR OF AGE

152 -12 (86) 2025 - Boltaboev T.T., Eshbaev E.A. - PATHOMORPHOLOGY IMMUNOHISTOCHEMICAL ASPECTS OF REGIONAL LYMPH NODES IN DEVELOPED PERITONITIS IN CHILDREN UNDER ONE YEAR OF AGE

PATHOMORPHOLOGY IMMUNOHISTOCHEMICAL ASPECTS OF REGIONAL LYMPH NODES IN DEVELOPED PERITONITIS IN CHILDREN UNDER ONE YEAR OF AGE

Boltaboev T.T. - Fergana Public Health Medical Institute of Uzbekistan

Eshbaev E.A. - Tashkent State Medical University

Resume

In the case of peritonitis in infants under one year of age, immunohistochemical studies are important in determining the morphological changes in the mesenteric lymph nodes, the phenotype of lymphocytes that is increased, the proliferative activity of mesenchymal cells, and the degree of apoptosis. In this case, T and B lymphocytes were examined for CD 3, CD4, and CD20 markers, and the results obtained were used to determine the degree of expression of immunomarkers. In 28-day-old and 6-month-old infants, acute deficiency of T lymphocytes prevailed, while in 12-month-old infants, a predominance of B lymphocyte deficiency and moderate expression of T lymphocytes were determined.

Keywords: lymph node, peritonitis, lymphoid follicle, immunodeficiency, infant.

First page

858

Last page

863

For citation:Boltaboev T.T., Eshbaev E.A. - PATHOMORPHOLOGY IMMUNOHISTOCHEMICAL ASPECTS OF REGIONAL LYMPH NODES IN DEVELOPED PERITONITIS IN CHILDREN UNDER ONE YEAR OF AGE//New Day in Medicine 12(86)2025 858-863 https://newdayworldmedicine.com/en/new_day_medicine/12-86-2025

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