19 -2 (88) 2026 - Shokirova S.M., Ergasheva D. - HEMATOLOGICAL AND PATHOMORPHOLOGICAL ASPECTS OF PLACENTAL CIRCULATORY PATHOLOGY AND THEIR ROLE IN THE PREVENTION OF PERINATAL COMPLICATIONS

HEMATOLOGICAL AND PATHOMORPHOLOGICAL ASPECTS OF PLACENTAL CIRCULATORY PATHOLOGY AND THEIR ROLE IN THE PREVENTION OF PERINATAL COMPLICATIONS

Shokirova S.M. - Andijan State Medical Institute

Ergasheva D. - Andijan State Medical Institute

Resume

Disorders of placental blood circulation are among the most important causes of perinatal complications, including fetal growth restriction (FGR), preeclampsia, preterm birth, antenatal hypoxia, stillbirth, and neonatal neurological sequelae. In recent years, the concepts of maternal vascular malperfusion (MVM) and fetal vascular malperfusion (FVM) have been standardized according to the Amsterdam consensus, which has significantly improved pathomorphological diagnosis, clinical risk assessment, and the determination of preventive strategies in subsequent pregnancies. This review analyzes hematological changes associated with MVM/FVM (hemostatic imbalance, platelet indices, and markers of hypercoagulability), as well as their pathomorphological features (infarctions, intervillous thrombi, decidual arteriopathy, avascular villi, etc.) and their practical significance in the prevention of perinatal complications.

Keywords: placenta, maternal vascular malperfusion, fetal vascular malperfusion, hemostasis, platelets, infarction, intervillous thrombus, Doppler, preeclampsia, fetal growth restriction (FGR), prevention.

First page

94

Last page

97

For citation:Shokirova S.M., Ergasheva D. - HEMATOLOGICAL AND PATHOMORPHOLOGICAL ASPECTS OF PLACENTAL CIRCULATORY PATHOLOGY AND THEIR ROLE IN THE PREVENTION OF PERINATAL COMPLICATIONS//New Day in Medicine 2(88)2026 94-97 https://newdayworldmedicine.com/en/new_day_medicine/2-88-2026

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