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  • 23 -1 (87) 2026 - Khaydarova N.B. - PREGNANCY ASSOCIATED WITH UTERINE LEIOMYOMA: CLINICAL COURSE AND ASSESSMENT OF OBSTETRIC RISKS

23 -1 (87) 2026 - Khaydarova N.B. - PREGNANCY ASSOCIATED WITH UTERINE LEIOMYOMA: CLINICAL COURSE AND ASSESSMENT OF OBSTETRIC RISKS

PREGNANCY ASSOCIATED WITH UTERINE LEIOMYOMA: CLINICAL COURSE AND ASSESSMENT OF OBSTETRIC RISKS

Khaydarova N.B. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Objective To evaluate the diagnostic significance of immunological markers in predicting early and late obstetric complications in pregnant women with uterine leiomyoma. Materials and Methods: the study was conducted at the gynecology department of the Bukhara City Maternity Complex. A total of 38 pregnant women diagnosed with uterine leiomyoma and receiving observation and treatment were comprehensively examined. All participants underwent assessment of anamnestic data, clinical and functional parameters, as well as molecular-genetic investigations. Results: the results demonstrated that the mean serum IgA level in the control group was 1.85 ± 0.12 g/L, which was within the reference range (1.46–2.22 g/L). In pregnant women with uterine leiomyoma, serum IgA levels were found to be 1.62 times higher compared to the control group (p < 0.05). Additionally, the mean IgA concentration in patients exceeded the upper limit of the normal range by 1.35 times (p < 0.05). Conclusion: according to the findings, the assessment of immunological markers in pregnant women with uterine leiomyoma is an effective method for evaluating disease progression and early prediction of obstetric complications. Immunological monitoring not only provides insight into the course of pregnancy but also enables individualized planning of preventive and therapeutic measures.

Keywords: myomatous nodule, immune system, obstetric complications, immunological monitoring

First page

123

Last page

126

For citation: Khaydarova N.B. - PREGNANCY ASSOCIATED WITH UTERINE LEIOMYOMA: CLINICAL COURSE AND ASSESSMENT OF OBSTETRIC RISKS//New Day in Medicine 1(87)2026 123-126 https://newdayworldmedicine.com/en/new_day_medicine/1-87-2026

List of References

  1. Nаrzullаеvа, N. S., Musаkhоdzhаеvа, D. А., Аbdurаkhmаnоv, M. M., Ikhtiуаrоvа, G. А. (2019). Суtоkinе dуnаmiсs аs а rеsult оf рhуtо flаvаnоid ехроsurе in wоmеn with utеrinе mуоmа. Russiаn Jоurnаl Оf Immunоlоgу, 2019;22(2-1):435-437. dоi: 10.31857/S102872210006922-9
  2. Nаrzullаеvа N.S., Musаkhоdzhаеvа D.а., аbdurаkhmаnоv M.M., Ikhtiуаrоvа G.а. Cуtоkinе dуnаmics аs а rеsult оf рhуtо-flаvаnоid ехроsurе in wоmеn with utеrinе mуоmа // Russiаn Jоurnаl оf Immunоlоgу. 2019;22(2-1):435-437. dоi: 10.31857/S102872210006922-9
  3. Nаrzullаеvа N.S. (2021). Gуnеcоlоgicаlаnd sоmаtic histоrу оf wоmеn with utеrinе mуоmа аccоrding tо rеtrоsреctivе аnаlуsis. Акуш., гинекол., перинатол 2021;(2):86.
  4. Nаrzullаеvа, N. S., Iхtiуаrоvа, G. а., & Sh, B. а. (2022). Clinicаl аnd Immunоlоgуcаl аsреcуs оf Lеоmiоmа with Еndоmеtritis. Cеntrаl аsiаn Jоurnаl оf Mеdicаl аnd Nаturаl Sciеncе 2022;3(4):301-305.
  5. Nаrzullауеvа, N. S. (2022). Innоvаtivе mеthоds оf diаgnоsis аnd trеаtmеnt in wоmеn with infеrtilitу аssоciаtеd with utеrinе fibrоids. Jоurnаl оf Рhаrmаcеuticаl Nеgаtivе Rеsults,2022; 3313-3321 pp.
  6. Sоng H., Lu D., Nаvаrаtnаm K.еt аl. аrоmаtаsе inhibitоrs fоr utеrinе fibrоids // Cоchrаnе Dаtаbаsе Syst Rеv. 2013;10:CD009505.
  7. Абрамова С.В., Миронова И.Н., Курганова О.Ю. и др. Клинико-эпидемиологические аспекты миомы матки (обзор литературы) // Бюллетень науки и практики. 2018;4(4):69-74.
  8. Агабабян Л.Р., Хамзаев Ф.И. Метаболические показатели у женщин с миомой матки на фоне избыточной массы тела // В сборнике: Достижения вузовской науки 2018. Сборник статей II Международного научно-исследовательского конкурса. –М., 2018; 224-227 стр.
  9. Агафонова Д.Д. Эффективность эмболизации маточных артерий в лечении миомы матки // В сборнике: Материалы 69-й межвузовской (IV Всероссийской) итоговой научной студенческой конференции с международным участием, посвященной 70-летию Победы в Великой Отечественной войне. –М., 2015; 3-4 стр.
  10. Бабаджанова Г.С., Тухтамишева Н.О. Современный взгляд на диагностику и лечение миомы матки у женщин репродуктивного возраста // Биология и интегративная медицина. 2017;2:64-79.
  11. Балашова Е.О., Супрунюк В.В. Эндоскопическое лечение миомы матки // Студенческий форум. 2018;7(28):16-18.
  12. Sparic R, Mirkovic L, Malvasi A, Tinelli A. Epidemiology of uterine myomas: a review Int J Fertil Steril. 2016;9(4):424-435

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