45 -2 (88) 2026 - Mamajonova S.O. - REGENERATIVE CHANGES IN VAGINAL ATROPHY IN WOMEN OF REPRODUCTIVE AGE

REGENERATIVE CHANGES IN VAGINAL ATROPHY IN WOMEN OF REPRODUCTIVE AGE

Mamajonova S.O. - Andijan State Medical Institute

Resume

Women of reproductive age often experience undesirable clinical manifestations that significantly reduce their quality of life, especially in the context of dysbiotic disturbances in the vaginal microbiota. In recent years, an increase in the incidence of such symptoms has been observed, particularly in patients with a complicated obstetric history, including the birth of a large fetus.The aim of this study was to identify early morphofunctional changes in the structural components of the atrophic vaginal mucosa. The identified morphological features of fibroblasts indicate enhanced functional activity aimed at remodeling the extracellular matrix, increasing the mechanical strength of connective tissue, and stimulating epithelial proliferation and maturation through improved trophism and delivery of biologically active factors through the newly formed vascular network.Thus, the study revealed activation of regenerative processes, manifested both in connective tissue—through neoangiogenesis, the formation of new papillae and collagen structures—and in the epithelial layer, accompanied by its thickening and increased desquamation of superficial cells of the vaginal mucosa.

Keywords: vaginal atrophy, fractional CO2 laser, laser treatment, regenerative treatment.

First page

217

Last page

221

For citation:Mamajonova S.O. - REGENERATIVE CHANGES IN VAGINAL ATROPHY IN WOMEN OF REPRODUCTIVE AGE//New Day in Medicine 2(88)2026 217-221 https://newdayworldmedicine.com/en/new_day_medicine/2-88-2026

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