• Home
  • NEW DAY MEDICINE
  • 12 (86) 2025
  • 165 -12 (86) 2025 - Kasimov N.A. - PERSONALIZED THERAPEUTIC AND DIAGNOSTIC ALGORITHM AND CLINICAL JUSTIFICATION OF DIFFERENTIATED SURGICAL TECHNIQUES IN PATIENTS WITH INFECTED PANCREATIC NECROSIS AND DIABETES MELLITUS

165 -12 (86) 2025 - Kasimov N.A. - PERSONALIZED THERAPEUTIC AND DIAGNOSTIC ALGORITHM AND CLINICAL JUSTIFICATION OF DIFFERENTIATED SURGICAL TECHNIQUES IN PATIENTS WITH INFECTED PANCREATIC NECROSIS AND DIABETES MELLITUS

PERSONALIZED THERAPEUTIC AND DIAGNOSTIC ALGORITHM AND CLINICAL JUSTIFICATION OF DIFFERENTIATED SURGICAL TECHNIQUES IN PATIENTS WITH INFECTED PANCREATIC NECROSIS AND DIABETES MELLITUS

Kasimov N.A. - Andijan State Medical Institute

Resume

This scientific article presents a personalized therapeutic-diagnostic algorithm developed by the authors for patients with infected pancreatic necrosis (IPN) and diabetes mellitus (DM). According to the algorithm, the treatment strategy for patients with low, high, and critical risk of IPN in the context of DM is analyzed, depending on the intensity of pancreatic necrobiosis according to the PN scale. Overall, the results of clinical investigations demonstrated that the therapeutic-diagnostic algorithm allows for determining the choice of surgical treatment—from a wait-and-see approach to minimally invasive interventions and active surgery. The therapeutic-diagnostic algorithm provides a basis for its clinical implementation in patients with IPN and concomitant DM.

Keywords: infected pancreatic necrosis, diabetes mellitus, therapeutic-diagnostic algorithm, personalized approach, surgical treatment.

First page

940

Last page

951

For citation:Kasimov N.A. - PERSONALIZED THERAPEUTIC AND DIAGNOSTIC ALGORITHM AND CLINICAL JUSTIFICATION OF DIFFERENTIATED SURGICAL TECHNIQUES IN PATIENTS WITH INFECTED PANCREATIC NECROSIS AND DIABETES MELLITUS //New Day in Medicine 12(86)2025 940-951 https://newdayworldmedicine.com/en/new_day_medicine/12-86-2025

List of References

  1. Батурина Я. А., Килеева Е. Л., Сахапова Л. М., Михайлов А. Ю. ОП в формировании СД 3 типа // Дневник науки. 2025;5(101).
  2. Жуков А. В., Грицан А. И., Беляев К. Ю., Беляева И. П. Сравнительный анализ методов оценки энергетической потребности пациентов с панкреатогенным сепсисом // Анестезиология и реаниматология (Медиа Сфера). 2025;3:26-33.
  3. Челяпина Т.П., Хрипун А.И., Алимов А.Н. и др. Эндоскопическая ультрасонография как эффективный инструмент для прогнозирования осложнений билиарного панкреатита // Доказательная гастроэнтерология. 2025;14(3):22-28.
  4. Шахова М. С., Шутеева Д. П., Литвинов С. А. Ближайшие результаты хирургического лечения больных с тяжелым острым панкреатитом // Биология и интегративная медицина. 2025;3(75):190-197.
  5. Cribari C., Tierney J., LaGrone L. Managing Complicated Pancreatitis with More Knowledge and a Bigger Toolbox! // Trauma Surg. Acute Care Open. 2025;10(1):e001798.
  6. Di Mauro D., Reece-Smith A., Njere I., et al. Eight-Years’ Experience of the Interventional and Non-Interventional Treatment of Pancreatic and Peripancreatic Necrosis in Patients with Severe Acute Pancreatitis Secondary to Gallstones and Alcohol Abuse: A Single-Centre Analysis // Acta Chir. Belg. 2025;125(5):244-253.
  7. Gala K., Storm A.C. Nature's Cystenterostomy: Spontaneous Pancreaticocolonic Fistulae Formation in Infected Pancreatic Walled-Off Necrosis // Am. J. Gastroenterol. 2025;120(11): 24-71.
  8. Mahapatra S.J., Shah R. Tailoring endoscopy for infected pancreatic necrosis: DEN or PEN or combined? // Pancreatology. 2025;25(1):3-4.
  9. Makhdoum A.R., Gholamhosseini A., Ghorani M., et al. Molecular Surveillance and Genetic Characterization of Infectious Pancreatic Necrosis Virus in Rainbow Trout Farms of East Azerbaijan, Iran // Res. Vet. Sci. 2025;196:105-894.
  10. Munke A., Ahmed Abdelrahim Gamil A., Mikalsen A.B., et al. Structure of the T=13 Capsid of Infectious Pancreatic Necrosis Virus (IPNV) – A Salmonid Birnavirus // J. Virol. 2025;99(2):e0145424.
  11. Pauw H.S., Timmerhuis H.C., Boxhoorn L., et al. Predictors for Successful Treatment of Infected Necrotizing Pancreatitis with Antibiotics Alone: A Nationwide Prospective Cohort // Ann. Surg. 2025;282(5):860-867.
  12. Rana R., Mahapatra S.J., Garg P.K. Endoscopic Interventions for Managing Pancreatic Fluid Collections Associated with Acute Pancreatitis: A State-of-the-Art Review // Indian J. Gastroenterol. 2025;44(6):777-798.
  13. Sahu S.K., Giri S., Das S., et al. Approach to the Diagnosis and Management of Infected Pancreatic Necrosis: A Narrative Review // Cureus. 2025;17(4):e83020.
  14. Satwick B.K., Mathur S.K., Patankar R. Nephroscope-Assisted Debridement of Pancreatic Necrosis Using the Palanivelu Hydatid Trocar Cannula System: A Novel Technique // Cureus. – 2025;17(5):e83851.
  15. Zhang Y., Wen S., Zhao G., Cui Y. Risk Factors for Peripancreatic and Pancreatic Infection of Acute Pancreatitis and the Development of a Clinical Prediction Model // Medicine (Baltimore). – 2025;104(21):e42595.

    file

    download