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  • 26 -1 (87) 2026 - Ermatov B.B. - OSTEOARTICULAR TUBERCULOSIS IN ASSOCIATION WITH HIV INFECTION: FEATURES OF PREVALENCE, TRANSMISSION, AND THE COURSE OF THE TUBERCULOUS PROCESS

26 -1 (87) 2026 - Ermatov B.B. - OSTEOARTICULAR TUBERCULOSIS IN ASSOCIATION WITH HIV INFECTION: FEATURES OF PREVALENCE, TRANSMISSION, AND THE COURSE OF THE TUBERCULOUS PROCESS

OSTEOARTICULAR TUBERCULOSIS IN ASSOCIATION WITH HIV INFECTION: FEATURES OF PREVALENCE, TRANSMISSION, AND THE COURSE OF THE TUBERCULOUS PROCESS

Ermatov B.B. - Republican specialized phthisiatry and pulmonology scientific and practical medical center

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The study analyzed medical records, clinical course, diagnostic findings, and treatment data of 99 (100%) patients who received inpatient care at the Republican Specialized Scientific and Practical Medical Center of Phthisiology and Pulmonology, as well as at the Jizzakh Regional Center of Phthisiology and Pulmonology during the period 2012–2023. The main group consisted of 47 (47.5%) patients with osteoarticular tuberculosis (OAT) occurring in the setting of HIV infection and AIDS (comorbid course). The control group included 52 (52.5%) patients with osteoarticular tuberculosis without HIV infection. The patients’ age ranged from 45 to 69 years, with a mean age of 45.9 ± 1.84 years. Males accounted for 56 (56.6%) patients and females for 43 (43.4%). Analysis of sex distribution showed that in the main group, males were affected 1.3 times more frequently than females. Among patients with HIV infection, osteoarticular tuberculosis was more commonly observed in young adults aged 18–44 years (57.4%), as well as in middle-aged individuals aged 45–59 years (42.6%). Assessment of epidemiological history revealed that 87.2% of HIV-infected patients denied contact with individuals with tuberculosis; in the control group, this proportion was 84.6%. In 83.3% of patients with combined OAT and HIV infection, the disease developed within 12 months. Polylocal involvement was identified in 27.7% of cases, and bilocal involvement in 34%. In 60.6% of patients, tuberculosis-related involvement of three or more vertebral bodies was recorded.

Keywords: osteoarticular tuberculosis, HIV infection, combined forms, prevalence, clinical features.

First page

136

Last page

142

For citation:Ermatov B.B. - OSTEOARTICULAR TUBERCULOSIS IN ASSOCIATION WITH HIV INFECTION: FEATURES OF PREVALENCE, TRANSMISSION, AND THE COURSE OF THE TUBERCULOUS PROCESS//New Day in Medicine 1(87)2026 136-142 https://newdayworldmedicine.com/en/new_day_medicine/1-87-2026

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