31 -1 (87) 2026 - U.M. Voseeva, A.T. Djurabekova - DIAGNOSTIC SIGNIFICANCE OF COMPREHENSIVE EXAMINATION OF CHILDREN WITH CONGENITAL ANOMALIES OF THE BRAIN AND VISUAL ORGAN

DIAGNOSTIC SIGNIFICANCE OF COMPREHENSIVE EXAMINATION OF CHILDREN WITH CONGENITAL ANOMALIES OF THE BRAIN AND VISUAL ORGAN

U.M. Voseeva - Samarkand State Medical University

A.T. Djurabekova - Samarkand State Medical University

Resume

Congenital anomalies of the brain and organ of vision represent a heterogeneous group of pathological conditions formed as a result of disruptions in embryogenesis at various stages of ontogenetic development. The pathogenetic basis of these disorders is associated with the disregulation of molecular-genetic mechanisms of morphogenesis, which control the processes of neurulation, the formation of the eyeball, and the differentiation of neuroectodermal derivatives. Epidemiological data indicate that isolated anomalies of the central nervous system occur at 2-3 per 1000 newborns, while congenital defects of the organ of vision are diagnosed at 1.5-2.5 per 10,000 children.

Keywords: congenital brain anomalies, congenital anomalies of the organ of vision, comprehensive diagnostics, neurovisualization, ophthalmoscopy, magnetic resonance imaging

First page

175

Last page

178

For citation:U.M. Voseeva, A.T. Djurabekova - DIAGNOSTIC SIGNIFICANCE OF COMPREHENSIVE EXAMINATION OF CHILDREN WITH CONGENITAL ANOMALIES OF THE BRAIN AND VISUAL ORGAN//New Day in Medicine 1(87)2026 175-178 https://newdayworldmedicine.com/en/new_day_medicine/1-87-2026

List of References

1. Baldassari S., Stephenson S.E.M. Congenital malformations of the central nervous system in children: diagnostic challenges. Journal of Pediatric Neurology. 2022; 20(3): 145–152.
2. Bernardes da Cunha S., Silva R., Monteiro M. Congenital brain anomalies: clinical and neuroimaging correlations. Child’s Nervous System. 2023; 39(4): 987–995.
3. Guarnera A., Valente P., Pasquini L. Genetic and structural basis of combined brain and ocular malformations in children. European Journal of Paediatric Neurology. 2024; 38: 12–19.
4. Denisova E.V. Congenital malformations of the visual analyzer in pediatric neurology practice. Neurology, Neuropsychiatry, Psychosomatics. 2018; 10(2): 45–51.
5. Голосная Г.С. Врожденные аномалии центральной нервной системы у детей: клинико-диагностические аспекты. Журнал неврологии и психиатрии им. С.С. Корсакова. 2023; 123(6): 34–40.
6. Шахмалиева А.М., Гидаятзаде С.С. Врожденные пороки развития головного мозга и органа зрения у детей. Неврологический вестник. 2017; 49(2): 58–63.
7. Rahimova K.E. Genetic risk factors of congenital brain anomalies in children. Central Asian Journal of Medical Sciences. 2022; 8(1): 21–27.
8. Ахмедов К., Турсунходжаева Ш. Врожденная гидроцефалия у детей: диагностика и клинические формы. Педиатрия. 2021; 100(4): 72–77.
9. Имамбетова А.С. Ретинопатия и врожденные аномалии органа зрения у детей раннего возраста. Офтальмологический журнал. 2020; 6: 41–46.
10. Бобоев А.Т., Джурабекова А.Т. Полиморфизмы генов фолатного цикла и риск врожденных пороков развития нервной системы. Медицинская генетика. 2025; 24(2): 89–96.
11. Джурабекова А.Т. Современные подходы к диагностике врожденных заболеваний нервной системы у детей. Вестник Самаркандского государственного медицинского университета. 2021; 4: 15–20.
12. Stephenson S.E.M., Baldassari S. Neurodevelopmental outcomes in children with congenital brain malformations. Developmental Medicine Child Neurology. 2022; 64(5): 603–609.

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