186 -2 (88) 2026 - Mamajonova Z.Sh., Egamberdiyeva D.A. - PROGNOSTIC SIGNIFICANCE OF CORONARY CALCIFICATION IN PATIENTS WITH CHRONIC CORONARY SYNDROME AND OBESITY

PROGNOSTIC SIGNIFICANCE OF CORONARY CALCIFICATION IN PATIENTS WITH CHRONIC CORONARY SYNDROME AND OBESITY

Mamajonova Z.Sh. - Tashkent State Medical University

Egamberdiyeva D.A. - Tashkent State Medical University

Resume

Chronic coronary syndrome and obesity constitute a unified cardiometabolic continum characterized by inflammation, insulin resistance, and activation of vascular calcification pathways. The coronary artery calcium (CAC) score reflects cumulative atherosclerotic burden and is strongly associated with the risk of cardiovascular events. In patients with obesity, interpretation of CAC dynamics—particularly during lipid-lowering therapy—requires caution. Despite its high prognostic value, the clinical application of CAC in this population remains limited due to the lack of randomized trials and obesity-specific threshold values.

Keywords: Visceral obesity, coronary artery disease, atherosclerosis, coronary calcification

First page

1015

Last page

1022

For citation:Mamajonova Z.Sh., Egamberdiyeva D.A. - PROGNOSTIC SIGNIFICANCE OF CORONARY CALCIFICATION IN PATIENTS WITH CHRONIC CORONARY SYNDROME AND OBESITY//New Day in Medicine 2(88)2026 1015-1022 https://newdayworldmedicine.com/en/new_day_medicine/2-88-2026

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