31 -3 (89) 2026 - Negmatullayeva M.N., Najmetdinova D.F. - HEMODYNAMIC DISORDERS IN GESTATIONAL HYPERTENSIVE CONDITIONS IN PREGNANT WOMEN

HEMODYNAMIC DISORDERS IN GESTATIONAL HYPERTENSIVE CONDITIONS IN PREGNANT WOMEN

Negmatullayeva M.N. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Najmetdinova D.F. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Tuksanova D.I. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Ulugbekova B.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Gestational hypertensive disorders are currently among the most significant pregnancy pathologies and increase the risk of serious complications for both the mother and the fetus. Hemodynamic disturbances of the cardiovascular system play a key role in the development of these conditions. The aim of this study was to evaluate central hemodynamic parameters in pregnant women with gestational hypertension and assess their clinical significance.The results demonstrated a decrease in cardiac output, an increase in peripheral vascular resistance, and disruption of hemodynamic balance, which may lead to fetal hypoxia, placental insufficiency, and perinatal complications. Comprehensive monitoring of central hemodynamics and uteroplacental-fetal blood flow is crucial for early detection of preeclampsia and rational management of pregnancy.

Keywords: gestational hypertension, central hemodynamics, pregnancy, cardiac output, peripheral resistance, preeclampsia.

First page

189

Last page

196

For citation:Negmatullayeva M.N., Najmetdinova D.F., Tuksanova D.I., Ulugbekova B.U. - HEMODYNAMIC DISORDERS IN GESTATIONAL HYPERTENSIVE CONDITIONS IN PREGNANT WOMEN//New Day in Medicine 3(89)2026 189-196 https://newdayworldmedicine.com/en/new_day_medicine/3-89-2026

List of References

  1. Балушкина А.А., Тютюнник В.Л., Кан Н.Е., Харченко Д.К., Борис Д.А. Прогнозирование и лабораторная диагностика гипертензивных расстройств при беременности. РМЖ. Мать и дитя. 2019;2(2):89-94. DOI: 10.32364/2618-8430-2019-2-2-89-94.
  2. Гамзаева С.Э. Влияние артериальной гипертензии на механизмы формирования маточно-плацентарно-плодового кровотока// Фундаментальные исследования. 2013. № 9.С. 14-18. URL: https://fundamental-research.ru/ru/article/view?id=32168.
  3. Можинская Ю.В., Белик С.Н., Подгорный И.В., Евдокимова Е.Г. Особенности маточно-плацентарной гемодинамики и структурно-функциональных изменений в системе «мать–плацента–плод» при гипертонической болезни // Молодой ученый. 2016. № 18.1 (122.1). С. 60-62. URL: https://moluch.ru/archive/122/33735
  4. Никитаева А.П., Росюк Е.А., Вишнева Е.М. Влияние гестационной артериальной гипертензии на течение беременности и развитие осложнений со стороны матери и плода// Современные проблемы науки и образования.2023.№4. URL: https://science-education.ru/ru/article/view?id=32862
  5. Чулков В.С., Сюндюкова Е.Г., Чулков Вл.С., Тарасова О.А., Романюго Г.Д. Гипертензивные нарушения во время беременности и риск сердечно-сосудистых заболеваний. Профилактическая медицина. 2021;24(12):C.97104.
  6. Lemonnier M., Beucher G., Morello R., Herlicoviez M., Dreyfus M., Benoist G. Subsequent pregnancy outcomes after first pregnancy with severe preeclampsia and delivery before 34 weeks of gestation. J. Gynecol. Obstet. Biol. Reprod. (Paris). 2013; 42(2): P.174-83.
  7. Lazdam M., Davis E.F., Lewandowski A.J., Worton S.A., Kenworthy Y., Kelly B., Leeson P. Prevention of vascular dysfunction after preeclampsia: a potential long-term outcome measure and an emerging goal for treatment. J. Pregnancy. 2012; 2012: Article ID 704.P.146
  8. Khong S.L., Kane S.C., Brennecke S.P., da Silva Costa F. First-Trimester Uterine Artery Doppler Analysis in the Prediction of Later Pregnancy Complications. Dis. Markers. 2015;P. 679730.
  9. Lykke J.A., Bare L.A., Olsen J., Lagier R., Arellano A.R., Tong C., Paidas M.J., Langhoff-Roos J. Thrombophilias and adverse pregnancy outcomes: results from the Danish National Birth Cohort. J. Thromb. Haemost. 2012;10(7):P.1320–25.
  10. Magee L.A., Dadelszen P., Singer J., Lee T., Rey E. Can adverse maternal and perinatal outcomes be predicted when blood pressure becomes elevated? Secondary analyses from the CHIPS (Control of Hypertension In Pregnancy Study) randomized controlled trial. Acta Obstet. Gynecol. Scand. 2016;95(7):P.763–76.
  11. Tranquilli A.L., Dekker G., Magee L., Roberts J., Sibai B.M., Steyn W., Zeeman G.G., Brown M.A. The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP. Pregnancy Hypertens. 2014;4(2):P.97–104.
  12. Payne B., Hodgson S., Hutcheon J.A., Joseph K.S., Li J., Lee T., Magee L.A., Qu Z., von Dadelszen P.; PIERS Study Group. Performance of the full PIERS model in predicting adverse maternal outcomes in pre-eclampsia using patient data from the PIERS (Pre-eclampsia integrated estimate of risk) cohort, collected on admission. BJOG. 2013;120(1):P.113–18

    file

    download