• Home
  • NEW DAY MEDICINE
  • 2 (88) 2026
  • 206 -2 (88) 2026 - Abdikulova N.Kh., Umarova N.M. - CHANGES IN BLOOD ELEMENTAL COMPOSITION IN OSTEOPOROSIS IN PERIMENOPAUSAL WOMEN

206 -2 (88) 2026 - Abdikulova N.Kh., Umarova N.M. - CHANGES IN BLOOD ELEMENTAL COMPOSITION IN OSTEOPOROSIS IN PERIMENOPAUSAL WOMEN

CHANGES IN BLOOD ELEMENTAL COMPOSITION IN OSTEOPOROSIS IN PERIMENOPAUSAL WOMEN

Abdikulova N.Kh. - Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Center for Maternal and Child Health, Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics, Tashkent, Republic of Uzbekistan

Umarova N.M. - Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Center for Maternal and Child Health, Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics, Tashkent, Republic of Uzbekistan

Rustamova U.M. - Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Center for Maternal and Child Health, Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics, Tashkent, Republic of Uzbekistan

Resume

Introduction: the most common pathology in women during perimenopause is osteoporosis, which affects the quality of life. Recently, the problem of macro- and micronutrient deficiency in this pathology has attracted increasing attention. The aim of the study is to determine the features of the electrolyte composition in the blood of women with osteoporosis during perimenopause. Material and research methods: the study included 195 women aged 45 to 55 years. All patients underwent bone mineral density testing and biochemical blood tests to determine the levels of Ca, Na, K, P, Fe, Mg, and Zn. Research results: there is a progressive decrease in the levels of Ca, Fe, Mg, and Zn in the blood of women with osteopenia and osteoporosis. Conclusion: a decrease in the levels of macro- and micronutrients in a woman's body during perimenopause contributes to the development of osteopenia and, subsequently, to the incorrect treatment of osteoporosis.

Keywords: osteoporosis, perimenopause, deficiency of macro- and micronutrients.

First page

1135

Last page

1141

For citation:Abdikulova N.Kh., Umarova N.M., Rustamova U.M. - CHANGES IN BLOOD ELEMENTAL COMPOSITION IN OSTEOPOROSIS IN PERIMENOPAUSAL WOMEN//New Day in Medicine 2(88)2026 1135-1141 https://newdayworldmedicine.com/en/new_day_medicine/2-88-2026

List of References

  1. Азизова Г.Д. Полиморфизм генов в прогнозировании остеопоротических нарушений у женщин узбекской популяции в постменопаузе: автореф. дисс. ... канд. мед. наук. Ташкент; 2019. 28 с.
  2. Дыдыкина И.С., Дыдыкина П.С., Алексеева О.Г. Вклад микроэлементов (меди, марганца, цинка, бора) в здоровье кости: вопросы профилактики и лечения остеопении и остеопороза. Эндокринология. 2013;(Спецвып. 2 «Остеопороз»):42-49.
  3. Синяченко О.В., Климовицкий Ф.В., Морозюк Д.М., Ермолаева М.В., Ливенцова Е.В. Клинико-патогенетические особенности сниженной костной массы у постменопаузальных женщин. Боль. Суставы. Позвоночник. 2020;10(2):101-105. doi:10.22141/2224-1507.10.2.2020.206946.
  4. Bureau I, Anderson RA, Arnaud J, et al. Trace mineral status in postmenopausal women: impact of hormonal replacement therapy. J Trace Elem Med Biol. 2002;16(1):9-13.
  5. Das M, Cronin O, Keohane DM, Cormac EM, Nugent H, Nugent M, et al. Gut microbiota alterations associated with reduced bone mineral density in older adults. Rheumatology (Oxford). 2019;58(12):2295-2304. doi:10.1093/rheumatology/kez302.
  6. Harvey NC, Odén A, Orwoll E, Lapidus J, Kwok T, Karlsson MK. Measures of physical performance and muscle strength as predictors of fracture risk independent of FRAX, falls, and aBMD: a metaanalysis of the Osteoporotic Fractures in Men (MrOS) study. J Bone Miner Res. 2018;33(12):2150-2157. doi:10.1002/jbmr.3556.
  7. Lesnyak O, Bilezikian JP, Zakroyeva A, et al. Report on the Audit on Burden of Osteoporosis in Eight Countries of the Eurasian Region: Armenia, Belarus, Georgia, Moldova, Kazakhstan, the Kyrgyz Republic, the Russian Federation, and Uzbekistan. Arch Osteoporos. 2020;15(1):1-8.
  8. Moser-Veillon PB. Zinc needs and homeostasis during lactation. Analyst. 1995;120(3):895-897.
  9. Mutlu M, Argun M, Kilic E, et al. Magnesium, zinc and copper status in osteoporotic, osteopenic and normal postmenopausal women. J Int Med Res. 2007;35(5):692-695.
  10. Odabasi E, Turan M, Aydin A, et al. Magnesium, zinc, copper, manganese, and selenium levels in postmenopausal women with osteoporosis. Can magnesium play a key role in osteoporosis? Ann Acad Med Singapore. 2008;37(7):564-567.

    file

    download