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20 -4 (90) 2026 - A.R. Abdulkhakimov - A COMPREHENSIVE APPROACH TO THE PREVENTION OF PURULENT-INFLAMMATORY COMPLICATIONS IN PEDIATRIC SURGERY

A COMPREHENSIVE APPROACH TO THE PREVENTION OF PURULENT-INFLAMMATORY COMPLICATIONS IN PEDIATRIC SURGERY

A.R. Abdulkhakimov - Fergana Medical Institute of Public Health

Resume

Background. Purulent-inflammatory complications (PICs) in children with surgical pathologies account for up to 30% of all hospital-acquired infections in pediatric practice. Modifiable predictors of these complications—primarily anemia and microbiome barrier disruptions—offer opportunities for preventive intervention. Traditional medicine in Uzbekistan possesses extensive experience in nutritional correction of anemia and immune support using traditional foods and fermented dairy products, which now finds modern scientific validation. The rehabilitation stage holds significant but underutilized preventive potential. Aim. To evaluate the role of anemia and microbiome disorders as predictors of purulent-inflammatory complications; to justify the integration of traditional nutritional correction methods and probiotic support into the perioperative prevention protocol; to analyze deficiencies in the rehabilitation stage and substantiate an original (author's) rehabilitation protocol. Materials and Methods. A retrospective-prospective study of 613 patients (146 inpatients, 467 outpatients) was conducted at the Fergana City Children's Hospital between 2023 and 2025. The study included microbiological monitoring, multivariate analysis of predictors, assessment of nutritional and dietary history, and an audit of medical records for patients in the rehabilitation stage (n=93). Results. Anemia was established as an independent modifiable predictor of purulent-inflammatory complications. S. aureus was identified as the leading pathogen (93.8%), with no MRSA detected. The developed three-level prevention system (PBMB concept), incorporating nutritional correction of anemia and a probiotic component, resulted in a reduction of PIC frequency from 32.8% to 9.8% (p<0.001). Critical deficiencies were identified at the rehabilitation stage: parent education program coverage was only 12.8–29.5%, and wound microbiological monitoring was performed in only 6.3% of cases. The author’s rehabilitation protocol reduced the recurrence rate from 31.3% to 10.9% (p<0.01). Conclusion. The integration of traditional nutritional anemia correction, probiotic elements of fermented nutrition, and a standardized rehabilitation stage into a unified perioperative prevention system is a pathogenetically grounded, clinically effective, and economically affordable approach to reducing purulent-inflammatory complications in children with surgical pathology.

Keywords: purulent-inflammatory complications, pediatric surgery, anemia, predictor of complications, nutritional correction, probiotics, fermented products, traditional medicine, microbiome, rehabilitation, relapse prevention, telemonitoring.

First page

140

Last page

147

For citation:A.R. Abdulkhakimov - A COMPREHENSIVE APPROACH TO THE PREVENTION OF PURULENT-INFLAMMATORY COMPLICATIONS IN PEDIATRIC SURGERY//New Day in Medicine 4(90)2026 140-147 https://newdayworldmedicine.com/en/new_day_medicine/4-90-2026

List of References

  1. Musallam KM, Tamim HM, Richards T, Spahn DR, Rosendaal FR, Habbal A, et al. Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet. 2011;378(9800):1396–1407. doi:10.1016/S0140-6736(11)61381-0
  2. Fowler AJ, Ahmad T, Phull MK, Gillies MA, Pearse RM, Bromilow J, et al. Meta-analysis of the association between preoperative anaemia and mortality after surgery. Br J Surg. 2015;102(11):1314–1324. doi:10.1002/bjs.9861
  3. World Health Organization. Worldwide prevalence of anaemia 1993–2005: WHO global database on anaemia. Geneva: WHO Press; 2008.
  4. Jonsson K, Jensen JA, Goodson WH 3rd, Scheuenstuhl H, West J, Hopf HW, Hunt TK. Tissue oxygenation, anemia, and perfusion in relation to wound healing in surgical patients. Ann Surg. 1991;214(5):605–613. doi:10.1097/00000658-199111000-00011
  5. Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352(10):1011–1023. doi:10.1056/NEJMra041809
  6. Oppenheimer SJ. Iron and its relation to immunity and infectious disease. J Nutr. 2001;131(2 Suppl 2):616S–635S. doi:10.1093/jn/131.2.616S
  7. Richards T, Clevenger B, Keidan I, McIntyre L, Montague O, Cohen J, et al. PREVENTT: preoperative intravenous iron to treat anaemia in major surgery: a randomised controlled trial. Lancet. 2020;396(10259):1353–1361. doi:10.1016/S0140-6736(20)31539-7
  8. Hallberg L, Brune M, Rossander L. The role of vitamin C in iron absorption. Int J Vitam Nutr Res Suppl. 1989;30:103–108.
  9. Zarfeshany A, Asgary S, Javanmard SH. Potent health effects of pomegranate. Adv Biomed Res. 2014;3:100. doi:10.4103/2277-9175.129371
  10. Weimann A, Braga M, Carli F, Higashiguchi T, Hübner M, Klek S, et al. ESPEN guideline: clinical nutrition in surgery. Clin Nutr. 2017;36(3):623–650. doi:10.1016/j.clnu.2017.02.013

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