26 -4 (90) 2026 - Nurova G.U., Khursanov A.M. - POSTOPERATIVE REGENERATION OF THE NASAL MUCOSA AFTER SEPTOPLASTY AND EFFECTIVE TREATMENT METHODS (LITERATURE REVIEW)

POSTOPERATIVE REGENERATION OF THE NASAL MUCOSA AFTER SEPTOPLASTY AND EFFECTIVE TREATMENT METHODS (LITERATURE REVIEW)

Nurova G.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Khursanov A.M. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

TAfter surgical interventions, especially septoplasty and operations on the maxillary sinuses, temporary impairment of mucociliary clearance in the nasal mucosa is observed. Separation of the mucoperichondrial layer causes damage to the epithelium and ciliary apparatus, resulting in swelling, hyperemia, and exudation. Subsequently, restoration of epithelialization and ciliary function contributes to gradual normalization of mucociliary activity. During this period, maintaining nasal moisture, irrigation therapy, and the use of local medications are crucial. Hyaluronic acid–based preparations can protect the mucosa, maintain hydration, and stimulate reparative processes; however, sufficient clinical evidence of their effectiveness in nasal diseases is currently lacking.

Keywords: nasal mucosa, septoplasty, regeneration, mucociliary clearance, local treatment, hyaluronic acid

First page

156

Last page

161

For citation:Nurova G.U., Khursanov A.M. - POSTOPERATIVE REGENERATION OF THE NASAL MUCOSA AFTER SEPTOPLASTY AND EFFECTIVE TREATMENT METHODS (LITERATURE REVIEW)//New Day in Medicine 4(90)2026 156-161 https://newdayworldmedicine.com/en/new_day_medicine/4-90-2026

List of References

  1. Ardizzoni A, Neglia RG, Baschieri MC, Cermelli C, Karatozzolo M, Righi E, et al. The effect of hyaluronic acid on bacterial and fungal species, including clinically relevant opportunistic microorganisms. J Mater Sci Mater Med. 2011;22(10):2329–2338. doi:10.1007/s10856-011-4409-6
  2. Alekseenko S, Karpischenko S, Barashkova S. Comparative analysis of mucociliary clearance and mucosal morphology using high-speed videomicroscopy in children with acute and chronic rhinosinusitis. Am J Rhinol Allergy. 2021;35(5):656–663. doi:10.1177/1945892421991234
  3. Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P. Chronic rhinosinusitis: pathogenesis and current treatment strategies. Allergy. 2020;75(4):770–780. doi:10.1111/all.14078
  4. Baraniuk JN. Neural regulation of mucosal function: autonomic dysfunction in rhinitis. Curr Allergy Asthma Rep. 2018;18(4):23. doi:10.1007/s11882-018-0760-4
  5. Bernstein JM. The immunology of the nasal mucosa. Otolaryngol Clin North Am. 2016;49(1):27–42. doi:10.1016/j.otc.2015.09.001
  6. Берест И.Е. Макроскопическая оценка регенерации слизистой оболочки полости носа после травмы (экспериментальное исследование). Уральский медицинский журнал. 2023;22(4):69–76.
  7. Passali D, Damiani V, Passali FM, Passali GC. Nasal irrigation in upper airway diseases. Int J Immunopathol Pharmacol. 2015;28(1):3–8. doi:10.1177/0394632015578130
  8. Proctor DF, Andersen I. The Nose: Upper Airway Physiology and the Atmospheric Environment. Amsterdam: Elsevier; 2015.
  9. Klossek JM, Dubreuil C, Richet H. Postoperative care after nasal surgery. Eur Ann Otorhinolaryngol Head Neck Dis. 2018;135(1):29–34. doi:10.1016/j.anorl.2017.09.007
  10. Gelardi M, Taliente S, Fiorella ML, Fiorella R. Hyaluronic acid in the treatment of nasal diseases. Curr Allergy Asthma Rep. 2013;13(2):173–181. doi:10.1007/s11882-012-0321-8

    file

    download