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  • 91 -4 (90) 2026 - Avezova S.Y., Kuryazov Sh.R. - THE EFFECT OF URINARY KALLIDINOGENASE (KALGEN 0.15 PNA) ON TOTAL PERIPHERAL VASCULAR RESISTANCE IN PATIENTS WITH CEREBRAL INFARCTION

91 -4 (90) 2026 - Avezova S.Y., Kuryazov Sh.R. - THE EFFECT OF URINARY KALLIDINOGENASE (KALGEN 0.15 PNA) ON TOTAL PERIPHERAL VASCULAR RESISTANCE IN PATIENTS WITH CEREBRAL INFARCTION

THE EFFECT OF URINARY KALLIDINOGENASE (KALGEN 0.15 PNA) ON TOTAL PERIPHERAL VASCULAR RESISTANCE IN PATIENTS WITH CEREBRAL INFARCTION

Avezova S.Y. - Urgench Branch of Tashkent State Medical University

Kuryazov Sh.R. - Specialized Scientific and Practical Medical Center for Cardiology and Cardiac Surgery of the Aral Sea Region

Resume

Objective: To evaluate the effect of urinary kallidinogenaze (Kalgen 0.15 PNA) on total peripheral vascular resistance in patients with cerebral infarction. Methods:All patients were divided into 2 groups: the control group, which included 32 patients receiving traditional therapy, and the study group, which included the remaining 32 patients who, in addition to the specified therapy, received Kalgen 0.15 PNA. Total peripheral vascular resistance (TPCR) was calculated using the formula. Results: Kalgen had a positive effect on TPCR in patients in the study group. In almost all patients, a decrease in TPCR was observed against the background of ongoing therapy as early as the 3rd day, without the use of antihypertensive drugs. Conclusions: Kalgen 0.15 PNA (urinary kallidinogenaze) reduces vascular resistance in brain infarction at earlier stages, contributing to improved perfusion of ischemic brain areas (penumbra zones)

Key words: ischemic stroke, total peripheral vascular resistance, urinary kallidinogenase, kinin-kallikrein system, blood pressure.

First page

592

Last page

597

For citation:Avezova S.Y., Kuryazov Sh.R. - THE EFFECT OF URINARY KALLIDINOGENASE (KALGEN 0.15 PNA) ON TOTAL PERIPHERAL VASCULAR RESISTANCE IN PATIENTS WITH CEREBRAL INFARCTION//New Day in Medicine 4(90)2026 592-597 https://newdayworldmedicine.com/en/new_day_medicine/4-90-2026

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