81 -5 (91) 2026 - J.T. Bafaev - ANALYSIS OF THE ASSOCIATION OF FACTOR G IN PATIENTS WITH RHEUMATOID ARTHRITIS AND METABOLIC SYNDROME

ANALYSIS OF THE ASSOCIATION OF FACTOR G IN PATIENTS WITH RHEUMATOID ARTHRITIS AND METABOLIC SYNDROME

J.T. Bafaev - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The present study assessed the prevalence of factor G in patients with rheumatoid arthritis (RA), depending on the presence of metabolic syndrome (MS), and compared it with a control group. The distribution of the studied factor was analyzed among patients with RA without MS, with a combination of RA and MS, as well as among the control group. It was found that factor G is characterized by a high prevalence in all the studied groups. The highest odds were found in patients with a combination of rheumatoid arthritis and metabolic syndrome. When comparing the main and control groups, no significant differences were found, which may indicate the absence of a pronounced association of factor G with the development of rheumatoid arthritis. The results obtained emphasize the need for further study of the role of genetic and metabolic factors in the pathogenesis of rheumatoid arthritis.

Keywords: rheumatoid arthritis, metabolic syndrome, factor G, genetic factors, prevalence, odds, association of risk factors.

First page

476

Last page

481

For citation:J.T. Bafaev - ANALYSIS OF THE ASSOCIATION OF FACTOR G IN PATIENTS WITH RHEUMATOID ARTHRITIS AND METABOLIC SYNDROME//New Day in Medicine 5(91)2026 476-481 https://newdayworldmedicine.com/en/new_day_medicine/5-91-2026

List of References

1. Рыкунова АЯ, Зверев ЯФ. Современные представления о патогенезе ревматоидного артрита. Патологическая физиология и экспериментальная терапия. 2024;68(4):59-70. DOI: 10.25557/0031-2991.2024.04.59-70.
2. Пасиешвили ЛМ, Синяченко ОВ. Ревматоидный артрит: дефиниция, клинико-патогенетические аспекты. Харьков: Издательский центр ХНМУ; 2018. 184 с.
3. Jahid M, Hossain MA, Islam MA, et al. Overview of rheumatoid arthritis and scientific understanding of the disease. Mediterr J Rheumatol. 2023;34(3):284-291. DOI: 10.31138/mjr.34.3.284.
4. Hasan AA, Khudhur HR, Hameed AK. Rheumatic autoimmune diseases (focus on RA): prevalence, types, causes and diagnosis. Karbala J Pharm Sci. 2022;(20):1-16.
5. Kumari M, Kumar A, Singh R, et al. Comprehensive review of rheumatoid arthritis: insights, challenges, and prospects. J Adv Zool. 2024;45(1):1-15.
6. Александров ВА. Особенности влияния метаболического синдрома на почечную функцию при ревматоидном артрите. Современные проблемы науки и образования. 2021;(1):92.
7. Попкова ТВ. Метаболический синдром при раннем ревматоидном артрите. Научно-практическая ревматология. 2010;48(6):23-29.
8. Трухан ДИ, Иванова ДС, Белус КД. Ревматоидный артрит и традиционные кардиоваскулярные факторы риска: актуальные аспекты реальной клинической практики. Consilium Medicum. 2020;22(1):19-25. DOI: 10.26442/20751753.2020.1.200037.
9. Song Y, Li J, Wu Y. Evolving understanding of autoimmune mechanisms and new therapeutic strategies of autoimmune disorders. Signal Transduct Target Ther. 2024;9(1):263. DOI: 10.1038/s41392-024-02031-z.
10. Piranavan P, Bhamra M, Perl A. Metabolic targets for treatment of autoimmune diseases. Immunometabolism. 2020;2(2):e200012. DOI: 10.20900/immunometab20200012.

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