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  • 9 -6 (92) 2026 - Safarova F.A. - MORPHOMETRIC CHANGES IN THE LIVER INDUCED BY COMBINED EXPOSURE TO ATMOSPHERIC PM2.5 AND TOBACCO SMOKE

9 -6 (92) 2026 - Safarova F.A. - MORPHOMETRIC CHANGES IN THE LIVER INDUCED BY COMBINED EXPOSURE TO ATMOSPHERIC PM2.5 AND TOBACCO SMOKE

MORPHOMETRIC CHANGES IN THE LIVER INDUCED BY COMBINED EXPOSURE TO ATMOSPHERIC PM2.5 AND TOBACCO SMOKE

Safarova F.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This article analyzes morphometric alterations in the liver caused by the combined exposure to atmospheric particulate matter (PM2.5) and tobacco smoke. Toxic compounds contained in PM2.5 and tobacco smoke enter the body through the respiratory system and induce oxidative stress, inflammatory responses, and cellular damage. Experimental studies demonstrate significant changes in hepatocyte diameter, sinusoidal dilatation, dystrophic alterations around central veins, and modifications in liver morphometric parameters. These findings are important for understanding the adverse effects of air pollution and tobacco smoke on liver structure and function.

Keywords: PM2.5, tobacco smoke, liver, morphometry, hepatocyte, oxidative stress, inflammation.

First page

44

Last page

46

For citation:Safarova F.A. - MORPHOMETRIC CHANGES IN THE LIVER INDUCED BY COMBINED EXPOSURE TO ATMOSPHERIC PM2.5 AND TOBACCO SMOKE//New Day in Medicine 6(92)2026 44-46 https://newdayworldmedicine.com/en/new_day_medicine/6-92-2026

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