50 -6 (92) 2026 - G’aybullaeva F.A., Ixtiyarova G.A. - REPRODUKTIV YOSHDAGI AYOLLARDA ENDOMETRIY PATOLOGIYALARINI KOMPLEKS MORFOLOGIK VA IMMUNOGISTOKIMYOVIY BAHOLASHNING KLINIK AHAMIYATI

REPRODUKTIV YOSHDAGI AYOLLARDA ENDOMETRIY PATOLOGIYALARINI KOMPLEKS MORFOLOGIK VA IMMUNOGISTOKIMYOVIY BAHOLASHNING KLINIK AHAMIYATI

G’aybullaeva F.A., Ixtiyarova G.A., Negmatullaeva M.N., Tuksanova D.I., Karimova N.N. - Abu Ali ibn Sino nomidagi Buxoro davlat tibbiyot instituti

Rezyume

Mazkur ilmiy maqolada reproduktiv va perimenopauzal yoshdagi ayollarda uchraydigan endometriyning giperplastik va yallig‘lanishli patologiyalarining klinik-morfologik xususiyatlari o‘rganildi. Tadqiqot davomida surunkali endometrit, endometriy giperplaziyasi va endometrial poliplarga ega ayollarda klinik simptomatika, gormonal status, ultratovush ko‘rsatkichlari hamda immunogistokimyoviy markerlar o‘zaro taqqoslandi. Tadqiqotda 240 nafar ayol ishtirok etdi. Olingan natijalarga ko‘ra, CD138 markerining yuqori ekspressiyasi surunkali endometrit uchun eng sezgir diagnostik marker ekanligi aniqlandi. ER va PR reseptorlaridagi o‘zgarishlar proliferativ patologiyalar og‘irligi bilan bog‘liqligi qayd qilindi. Kompleks diagnostik yondashuv yordamida klinik tashxis aniqligi sezilarli oshdi va patologik jarayonlarni differensial baholash imkoniyati kengaydi.

Kalit so‘zlar: endometriy patologiyasi, surunkali endometrit, immunogistokimyo, CD138, giperplaziya, reproduktiv salomatlik, morfologiya, proliferatsiya, ultratovush diagnostikasi, gormonal disbalans.

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For citation:G’aybullaeva F.A., Ixtiyarova G.A., Negmatullaeva M.N., Tuksanova D.I., Karimova N.N. - REPRODUKTIV YOSHDAGI AYOLLARDA ENDOMETRIY PATOLOGIYALARINI KOMPLEKS MORFOLOGIK VA IMMUNOGISTOKIMYOVIY BAHOLASHNING KLINIK AHAMIYATI//New Day in Medicine 6(92)2026 304-308 https://newdayworldmedicine.com/en/new_day_medicine/6-92-2026

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