26 -7 (93) 2026 - Kasimova R.I., Amonov S.B. - SURXONDARYO VILOYATIDA DELTA-AGENTLI SURUNKALI B GEPATITI BILAN KASALLANGAN BEMORLARDA HBsAg NING OILA ICHIDA YUQISHI: KLINIK-EPIDEMIOLOGIK TAHLIL

SURXONDARYO VILOYATIDA DELTA-AGENTLI SURUNKALI B GEPATITI BILAN KASALLANGAN BEMORLARDA HBsAg NING OILA ICHIDA YUQISHI: KLINIK-EPIDEMIOLOGIK TAHLIL

Kasimova R.I., Amonov S.B. - Respublika ixtisoslashtirilgan epidemiologiya, mikrobiologiya, yuqumli va parazitar kasalliklar ilmiy-amaliy tibbiyot markazining Virusologiya ilmiy-tadqiqot instituti

Reyume

Surunkali B gepatit (HBV) dunyoda 254 million kishini qamrab olib, yiliga 800 mingdan ortiq oʻlimga sabab boʻladi. HDV bilan koinfeksiya kasallikni ogʻirlashtiradi, fibroz, sirroz va jigar saratoni xavfini oshiradi. Oila ichida yuqish (vertikal, gorizontal va jinsiy) HBV rezervuarini saqlashning asosiy mexanizmidir. Oila ichida yuqish darajasi mintaqaga qarab 8% dan 78% gacha oʻzgaradi. Vaksina mavjud boʻlsa-da, HBsAg-musbat bemorlarning oila aʼzolari yuqori xavf guruhida qolmoqda.

Kalit soʻzlar: Surunkali B gepatit, HDV bilan koinfeksiya, оila ichida yuqish

First page

178

Last page

183

For citation:Kasimova R.I., Amonov S.B. - SURXONDARYO VILOYATIDA DELTA-AGENTLI SURUNKALI B GEPATITI BILAN KASALLANGAN BEMORLARDA HBsAg NING OILA ICHIDA YUQISHI: KLINIK-EPIDEMIOLOGIK TAHLIL//New Day in Medicine 7(93)2026 178-183 https://newdayworldmedicine.com/en/new_day_medicine/7-93-2026

List of References

1. de Franchis R, D'Arminio A, Viganò F, Vecchi M, Rumi MG, Ronchi G, Primignani M, Del Ninno E. Intrafamilial spread of hepatitis B virus infection (role of chronic hepatitis and of the hepatitis B e antigen). Ric Clin Lab. 1981;11(2):151-158. doi: 10.1007/BF02886715.
2. Luong QA, Nguyen HAT, Huynh KM, et al. Molecular epidemiology and factors associated with HBV transmission among schoolchildren and household members in central Vietnam. Trop Med Health. 2026;54:89. doi: 10.1186/s41182-026-00959-x.
3. Gunardi H, Iskandar MY, Turyadi, Ie SI, Dwipoerwantoro PG, Gani RA, Muljono DH. Hepatitis B virus infection in children of HBV-related chronic liver disease patients: a study of intra-familial HBV transmission. Hepatol Int. 2017;11(1):96-104. doi: 10.1007/s12072-016-9764-z.
4. Salkic NN, Zerem E, Zildic M, Ahmetagic S, Cickusic E, Ljuca F. Risk factors for intrafamilial spread of hepatitis B in northeastern Bosnia and Herzegovina. Ann Saudi Med. 2009;29(1):41-45. doi: 10.4103/0256-4947.51821.
5. Lin CL, Kao JH. Intrafamilial transmission of hepatitis B virus infection. J Gastroenterol Hepatol. 2007;22(5):765-766. doi: 10.1111/j.1440-1746.2007.04825.x.
6. Kim YS, Ahn YO, Kim DW. Familial clustering of hepatitis B and C viruses in Korea. J Korean Med Sci. 1994;9(6):444-449. doi: 10.3346/jkms.1994.9.6.444.
7. François-Souquière S, Makuwa M, Bisvigou U, Kazanji M. Epidemiological and molecular features of hepatitis B and hepatitis delta virus transmission in a remote rural community in central Africa. Infect Genet Evol. 2016;39:12-21. doi: 10.1016/j.meegid.2015.12.021.
8. Sagnelli C, Sica A, Creta M, Calogero A, Ciccozzi M, Sagnelli E. Epidemiological and clinical aspects of hepatitis B virus infection in Italy over the last 50 years. World J Gastroenterol. 2022;28(26):3081-3091. doi: 10.3748/wjg.v28.i26.3081.
9. Paththamperuma S, Rajamanthri L, Pattiyakumbura T, Muthugala R. Intra-familial transmission dynamics of hepatitis B virus. J Microbiol Infect Dis. 2024;14(4):191-193. doi: 10.5455/JMID.20240710075307.
10. Avazova D, Kurbanov F, Tanaka Y, Sugiyama M, Radchenko I, Ruziev D, Musabaev E, Mizokami M. Hepatitis B virus transmission pattern and vaccination efficiency in Uzbekistan. J Med Virol. 2008;80(2):217-224. doi: 10.1002/jmv.21035.

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