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  • 69 -8 (94) 2026 - Khushbokov I.S., Djumanov K.N., Ibragimov A.I. - IMPROVING SURGICAL DECISION-MAKING IN PATIENTS WITH EXTRADURAL TUMORS OF THE SPINE

69 -8 (94) 2026 - Khushbokov I.S., Djumanov K.N., Ibragimov A.I. - IMPROVING SURGICAL DECISION-MAKING IN PATIENTS WITH EXTRADURAL TUMORS OF THE SPINE

IMPROVING SURGICAL DECISION-MAKING IN PATIENTS WITH EXTRADURAL TUMORS OF THE SPINE

Khushbokov I.S., Djumanov K.N., Ibragimov A.I. - Republican Specialized Scientific and Practical Center of Neurosurgery

Resume

Extradural spinal tumors are growths located outside the dura mater, most commonly found in the epidural space or within the vertebral bones. They differ from intradural tumors, which develop inside the dural sac. The vast majority of extradural spinal tumors are metastatic, arising from hematogenous spread of primary cancers such as those of the breast, lung, prostate, kidney, thyroid, as well as melanoma, lymphoma, myeloma, and various gastrointestinal malignancies. These tumors frequently cause pain, vertebral collapse, spinal instability, or neurological symptoms due to compression of nerve roots or the spinal cord. Primary extradural tumors are comparatively rare and may be either benign or malignant, with their clinical behavior and outcomes largely dependent on histological type. The histological characteristics of a tumor are crucial in guiding management, as they offer important prognostic insights and influence treatment decisions. Stratifying tumors by their aggressiveness—from indolent to rapidly progressive—helps predict postoperative survival and determines the extent of surgery and the need for additional therapies. Certain hypervascular metastases, including those from renal cell carcinoma, thyroid cancer, hepatocellular carcinoma, melanoma, and some giant cell tumors, carry an elevated risk of significant bleeding during surgery. Preoperative embolization can be a useful measure to minimize blood loss in these cases. Accurately determining whether a tumor is extradural or intradural, and pinpointing its exact position relative to the dura and spinal canal, is essential for choosing the most appropriate surgical technique and reducing the risk of complications. In the wider context of spinal metastatic disease, it is also important to differentiate spinal metastases from primary spinal tumors. Treatment typically addresses both the spinal lesion and the underlying systemic cancer, with objectives focused on alleviating pain, preserving neurological function, maintaining spinal stability, enhancing quality of life, and carefully weighing systemic therapies and radiation sensitivity against the potential risks of surgery.

Keywords: Extradural spinal tumors; Spine neoplasms; Spinal metastases; Spinal instability neoplastic score (SINS); Epidural spinal cord compression (ESCC); Bilsky classification; NOMS framework.

First page

508

Last page

517

For citation:Khushbokov I.S., Djumanov K.N., Ibragimov A.I. - IMPROVING SURGICAL DECISION-MAKING IN PATIENTS WITH EXTRADURAL TUMORS OF THE SPINE//New Day in Medicine 8(94)2026 508-517 https://newdayworldmedicine.com/en/new_day_medicine/8-94-2026

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