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  • 57 -9 (95) 2026 - Abdumajitova A.J., Yaxyoyeva X.Sh. - SUBKLINIK GIPOTIREOZDA ICHAK MIKROBIOTASI VA MIKROBIAL METABOLITLAR PROFILINING TIREOID-GORMONAL HAMDA METABOLIK HOLAT BILAN O’ZARO BOG’LIQLIGI: ZAMONAVIY QARASHLAR

57 -9 (95) 2026 - Abdumajitova A.J., Yaxyoyeva X.Sh. - SUBKLINIK GIPOTIREOZDA ICHAK MIKROBIOTASI VA MIKROBIAL METABOLITLAR PROFILINING TIREOID-GORMONAL HAMDA METABOLIK HOLAT BILAN O’ZARO BOG’LIQLIGI: ZAMONAVIY QARASHLAR

SUBKLINIK GIPOTIREOZDA ICHAK MIKROBIOTASI VA MIKROBIAL METABOLITLAR PROFILINING TIREOID-GORMONAL HAMDA METABOLIK HOLAT BILAN O’ZARO BOG’LIQLIGI: ZAMONAVIY QARASHLAR

Abdumajitova A.J., Yaxyoyeva X.Sh. - Abu Ali ibn Sino nomidagi Buxoro davlat tibbiyot instituti

Rezyume

Subklinik gipotireoz (SG) tireotrop gormon (TTG) darajasining oshishi va erkin tiroksin (FT4) miqdorining me’yoriy chegaralarda saqlanishi bilan tavsiflanadi. So’nggi tadqiqotlar ichak mikrobiotasi va uning metabolitlari tireoid hamda metabolik gomeostaz bilan o’zaro bog’liq bo’lishi mumkinligini ko’rsatmoqda. Ushbu maqolada SGda ichak mikrobiotasi tarkibi, mikrobial metabolitlar, tireoid gormonlar hamda lipid va uglevod almashinuvi ko’rsatkichlari o’rtasidagi bog’liqlik zamonaviy ilmiy ma’lumotlar asosida tahlil qilindi. Mikrobiota hosil qiladigan qisqa zanjirli yog’ kislotalari, o’t kislotalari metabolitlari va boshqa biologik faol birikmalar ichak bareri, immun yallig’lanish va tireoid gormonlar metabolizmiga ta’sir ko’rsatishi mumkin. Shu sababli SGda mikrobiota, metabolom va tireoid-metabolik ko’rsatkichlarni kompleks baholash istiqbolli ilmiy yo’nalish hisoblanadi.

Kalit so’zlar: subklinik gipotireoz, ichak mikrobiotasi, mikrobial metabolitlar, TTG, FT4, qisqa zanjirli yog’ kislotalari, metabolomika.

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For citation:Abdumajitova A.J., Yaxyoyeva X.Sh. - SUBKLINIK GIPOTIREOZDA ICHAK MIKROBIOTASI VA MIKROBIAL METABOLITLAR PROFILINING TIREOID-GORMONAL HAMDA METABOLIK HOLAT BILAN O’ZARO BOG’LIQLIGI: ZAMONAVIY QARASHLAR//New Day in Medicine 9(95)2026 375-381 https://newdayworldmedicine.com/en/new_day_medicine/9-95-2026

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