3 -10 (96) 2026 - Mirzamudov H.G. - NOADEKVAT KOSMETIK MATERIALLAR KIRITILISHI NATIJASIDA YUZNING FASSIAL-LIGAMENTOZ TIZIMIDA YUZAGA KELADIGAN PATOMORFOLOGIK O’ZGARISHLAR VA ULARNING ENDOSKOPIK DISEKSIYA XAVFSIZLIGIGA TA’SIRI

NOADEKVAT KOSMETIK MATERIALLAR KIRITILISHI NATIJASIDA YUZNING FASSIAL-LIGAMENTOZ TIZIMIDA YUZAGA KELADIGAN PATOMORFOLOGIK O’ZGARISHLAR VA ULARNING ENDOSKOPIK DISEKSIYA XAVFSIZLIGIGA TA’SIRI

Mirzamudov H.G. - Akademik V.V.Vohidov nomidagi Respublika ixtisoslashtirilgan xirurgiya ilmiy-amaliy tibbiyot markazi eksperimental laboratoriyasi

Rezyume

Noadekvat kosmetik materiallar (gidroksiapatit, poliakrilamid gel, silikon, polilaktik kislota va boshqalar) kiritilgandan keyin yuzning fassial-ligamentoz tizimida yuzaga keladigan patomorfologik o’zgarishlarni o’rganish va ushbu o’zgarishlarning endoskopik diseksiya xavfsizligiga ta’sirini anatomik nuqtai nazardan asoslash. Tadqiqot 2023-2025 yillarda o’tkazilgan bo’lib, 47 nafar bemorda (32 ayol, 15 erkak; o’rtacha yosh 42,3±8,7) noadekvat kosmetik materiallar kiritilgandan keyin rivojlangan asoratlar tufayli endoskopik yuz ko’tarish operatsiyasi o’tkazilgan. Operatsiya davomida olingan to’qima biopsiyalari gistologik tekshiruvdan o’tkazilgan. Anatomik xavfsizlik chegaralari kadavr materiallarida (n=15) o'lchovlar o’tkazish orqali aniqlangan. Noadekvat kosmetik materiallar kiritilgandan keyin quyidagi patomorfologik o’zgarishlar aniqlangan: (1) sub-SMAS qatlamida diffuz fibroz (94,7%); (2) ligamentoz tuzilmalarning qalinlashishi va zichligining oshishi (87,2%); (3) granulematoz reaksiyalar (61,7%); (4) neyrovaskulyar to'plamlarning fibroz to'qima bilan o’ralishi (55,3%); (5) diseksiya qatlamlarining yo’qolishi (78,7%). Zigomatik va yuqori masseterik ligamentlar orasidagi masofa o'rtacha 13,3±3,8 mm ni tashkil etgan bo'lib, bu xavfsiz diseksiya koridorini belgilaydi. Noadekvat kosmetik materiallar kiritilishi natijasida yuzning fassial-ligamentoz tizimida rivojlanadigan fibroz o’zgarishlar endoskopik diseksiya xavfsizligini sezilarli darajada pasaytiradi. Xavfsiz diseksiya koridorlarini aniqlash va fibroz to’qimalarning tarqalishini operatsiyadan oldin baholash orqali asoratlar xavfini kamaytirish mumkin.

Kalit so’zlar: kosmetik materiallar, fassial-ligamentoz tizim, fibroz, endoskopik diseksiya, xavfsizlik chegaralari, patomorfologik o’zgarishlar

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For citation:Mirzamudov H.G. - NOADEKVAT KOSMETIK MATERIALLAR KIRITILISHI NATIJASIDA YUZNING FASSIAL-LIGAMENTOZ TIZIMIDA YUZAGA KELADIGAN PATOMORFOLOGIK O’ZGARISHLAR VA ULARNING ENDOSKOPIK DISEKSIYA XAVFSIZLIGIGA TA’SIRI//New Day in Medicine 10(96)2026 15-20 https://newdayworldmedicine.com/en/new_day_medicine/10-96-2026

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