5 -10 (96) 2026 - Sharobidinov B.T., Aliyev X.M. - ERKIN HARAKATDAGI VA GIPOKINEZIYA SHAROITIDAGI YUQORI YOG’LI OZIQLANISHDA JIGAR GISTOSTRUKTURASINING MORFOLOGIK O’ZGARISHLARI

ERKIN HARAKATDAGI VA GIPOKINEZIYA SHAROITIDAGI YUQORI YOG’LI OZIQLANISHDA JIGAR GISTOSTRUKTURASINING MORFOLOGIK O’ZGARISHLARI

Sharobidinov B.T., Aliyev X.M. - Andijon davlat tibbiyot instituti

Rezyume

Maqolada gipokineziya va yuqori kaloriyali yog'li ovqatlanish sharoitida oq kalamushlar jigarining gistostrukturasida yuzaga keladigan morfologik o'zgarishlar gematoksilin-eozin bo'yash usuli asosida o'rganilgan. Tadqiqotda 110 ta erkak jinsli oq kalamush nazorat, yog'li ovqatlanish (erkin harakat) va gipokineziya fonida yog'li ovqatlanish guruhlariga bo'lingan holda, 5, 10, 20, 30 va 60-sutkalik muddatlarda tekshirildi.Tadqiqot natijalaridan ma’lum bo’ldiki, erkin harakatlanishi cheklanmagan, kunlik ovqat ratsioniga qo'shimcha ravishda yog’ qo’shib berilgan guruhda tajriba davomida progressiv aralash (mikro- va makrovezikulyar) steatoz shakllandi, gipokineziya sharoitida faqat yog’ bilan boqilgan guruhda esa steatozdan tashqari mikrosirkulyator buzilish (sinusoidal kengayish, venoz to'laqonlilik), gidropik-ballon distrofiyasi va perivenulyar yallig'lanish reaktsiyasi ustunlik qilganligi aniqlandi. Olingan ma'lumotlar gipokineziyaning jigar patologiyasi rivojlanishida mustaqil patogenetik omil sifatidagi rolini tasdiqlaydi.

Kalit so'zlar: Gipokineziya, yog'li ovqatlanish, jigar, gistostruktura, steatoz, gepatotsit, gematoksilin-eozin, oq kalamush, noalkogolli yog'li jigar kasalligi

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For citation:Sharobidinov B.T., Aliyev X.M. - ERKIN HARAKATDAGI VA GIPOKINEZIYA SHAROITIDAGI YUQORI YOG’LI OZIQLANISHDA JIGAR GISTOSTRUKTURASINING MORFOLOGIK O’ZGARISHLARI//New Day in Medicine 10(96)2026 35-43 https://newdayworldmedicine.com/en/new_day_medicine/10-96-2026

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