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  • 4 -5 (43) 2022 — Adambaev Z.I., Kilichev I.A., — NEUROLOGICAL MANIFESTATIONS OF POST-COVID SYNDROME: STRUCTURE AND MEDICAL REHABILITATION

4 -5 (43) 2022 — Adambaev Z.I., Kilichev I.A., — NEUROLOGICAL MANIFESTATIONS OF POST-COVID SYNDROME: STRUCTURE AND MEDICAL REHABILITATION

NEUROLOGICAL MANIFESTATIONS OF POST-COVID SYNDROME: STRUCTURE AND MEDICAL REHABILITATION

Adambaev Z.I., Khorezm Regional Multidisciplinary Medical Center Urgench branch of the Tashkent Medical Academy, Uzbekistan

Kilichev I.A., Khorezm Regional Multidisciplinary Medical Center Urgench branch of the Tashkent Medical Academy, Uzbekistan

Nurjonov A.B., Khorezm Regional Multidisciplinary Medical Center Urgench branch of the Tashkent Medical Academy, Uzbekistan

Yarashev R.S. Khorezm Regional Multidisciplinary Medical Center Urgench branch of the Tashkent Medical Academy, Uzbekistan

Resume

505 patients with a confirmed diagnosis of SARS-CoV-2 (COVID-19) were examined and observed for 6 months to identify the structure of neurological manifestations of post-COVID syndrome. In the structure of neurological manifestations of the post-COVID syndrome, the following were identified: rapid fatigue, the symptom of “fog in the head”, memory loss, sleep disturbance, sweating, headache, impaired sense of smell and taste, anxiety and depression. During the medical rehabilitation of these patients in the form of succinic acid preparations, brain metabolites, stimulating antidepressants, sleeping pills, B vitamins, as well as antiviral, immunomodulatory, anti-inflammatory drugs, they have proven to be an effective medical rehabilitation of this category of patients.

Keywords: post-COVID syndrome, neurological manifestations, asthenia, cognitive impairment, smell and taste disorders, anxiety, depression, sleep disturbance.

First page

19

Last page

22

For citation: Adambaev Z.I., Kilichev I.A., Nurjonov A.B., Yarashev R.S. NEUROLOGICAL MANIFESTATIONS OF POST-COVID SYNDROME: STRUCTURE AND MEDICAL REHABILITATION //New Day in Medicine 5(43)2022 19-22 https://clck.ru/hEgwn

LIST OF REFERENCES:

  1. Aghagoli G., Gallo Marin B., Katchur N.J., et al. Neurological involvement in COVID-19 and potential mechanisms: A Review. Neurocrit Care. 2021 Jun; 34(3): 1062-1071. https://doi.org/10.1007/s12028-020-01049-4. PMID:32661794
  2. Barrantes F.J. Central nervous system targets and routes for SARS-CoV-2: current views and new hypotheses. ACS Chem Neurosci. 2020 Sep; 11(18): 2793-2803. https://doi.org/10.1021/acschemneuro.0c00434. Epub 2020 Aug 26. PMID:32845609
  3. Brann D.H., Tsukahara T., Weinreb C., et al. Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia. Sci Adv. 2020 Jul; 6(31): eabc5801. https://doi.org/10.1126/sciadv.abc5801. Epub 2020 Jul 24. PMID:32937591
  4. Garrigues E., Janvier P., Kherabi Y., et al. Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19. J Infect. 2020 Dec; 81(6): e4-e6. https://doi.org/10.1016/jjinf.2020.08.029. Epub 2020 Aug 25. PMID:32853602
  5. Goёrtz Y.M.J., Van Herck M., Delbressine J.M., et al. Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome? ERJ Open Res. 2020 Oct 26; 6(4): 005422020. https://doi.org/10.1183/23120541. 00542-2020. PMID:33257910
  6. Havervall S., Rosell A., Phillipson M., et al. Symptoms and functional impairment assessed 8 months after mild COVID-19 among health care workers. JAMA. 2021 May 18; 325(19): 2015-2016. https://doi.org/10.1001/jama. 2021.5612. PMID:33825846
  7. Huang C., Huang L., Wang Y., et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021 Jan 16; 397(10270): 220-232. https://doi.org/10.1016/S0140-6736(20)32656-8. Epub 2021 Jan 8. PMID:33428867
  8. Mao L., Jin H., WangM., et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol. 2020 Jun; 77(6): 683-690. https://doi.org/10.1001/jamaneurol.2020.1127. PMID:32275288
  9. Mazza M.G., De Lorenzo R., Conte C., et al. Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors. Brain Behav Immun. 2020 Oct; 89: 594-600. https://doi.org/10.1016/j.bbi.2020.07.037. Epub 2020 Jul 30. PMID:32738287
  10. Nalbandian A., Sehgal K., Gupta A., et al. Post-acute COVID-19 syndrome. Nat Med. 2021 Apr; 27(4): 601-615. https://doi.org/10.1038/s41591-021-01283-z. Epub 2021 Mar 22. PMID:33753937 
  11. Pezzini A., Padovani A. Lifting the mask on neurological manifestations of COVID-19. Nat Rev Neurol. 2020 Nov; 16(11): 636-644.  https://doi.org/10.1038/s41582-020-0398-3. Epub 2020 Aug 24. PMID:32839585
  12. Salmon-Ceron D., Slama D., De Broucker T., et al. Clinical, vi-rological and imaging profile in patients with prolonged forms of COVID-19: a cross-sectional study. J Infect 2021; 82(2): e1-4. https://doi.org/10.1016/jjinf.2020.12.002. Epub 2020 Dec 4. PMID:33285216
  13. Singal C.M.S., Jaiswal P., Seth P. SARS-CoV-2, more than a respiratory virus: its potential role in neuropathogenesis. ACS Chem Neurosci. 2020 Jul; 11(13): 1887-1899. https://doi.org/10.1021/acschemneuro.0c00251. Epub 2020 Jun 18. PMID:32491829
  14. Sudre C.H., Murray B., Varsavsky T., et al. Attributes and predictors of long COVID. Nat Med 2021 Apr; 27(4): 626-631. https://doi.org/10.1038/s41591-021-01292-y. Epub 2021 Mar 10. Erratum in: Nat Med. 2021 Jun; 27(6): 1116. PMID:33692530.
  15. Inoyatov A.SH., Ikhtiyarova G.A., Musaeva D.M., Karimova G.K., Assessment of the status of pregnant women with diabetes mellitus infected with covid-19//New Day in Medicine 2(30)2020 101-103 https://cutt.ly/gcQcYPa

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