66 -5 (43) 2022 — Khalilova F.A. — ASSESSMENT OF INTRACARDIAC HEMODYNAMICS AND ELECTROLYTE BALANCE IN VARIOUS HEMODYNAMIC TYPES OF CHRONIC HEART FAILURE ACCOMPANIED BY ANEMIA

ASSESSMENT OF INTRACARDIAC HEMODYNAMICS AND ELECTROLYTE BALANCE IN VARIOUS HEMODYNAMIC TYPES OF CHRONIC HEART FAILURE ACCOMPANIED BY ANEMIA

Khalilova F.A. Bukhara State Medical Institute,

Resume

Markers of renal fibrosis were evaluated in dynamics in order to study specific changes in the kidneys of patients with various hemodynamic types and functional classes of chronic heart failure with anemia and to evaluate the effectiveness of treatment with the drug exex. It was found that the marker of renal fibrosis TGF-β1 is 2591.0±108.4 and 755.0±18.87 PG/ml, respectively (p0,01), when the indicators of chronic heart failure in the blood were without anemia and anemia. This was evidenced by the process of fibrosis that occurred in the kidneys. After complex treatment with the addition of iron preparation, the TGF-β1 index decreased by 2.25 times (p0,01), the clinical condition, quality of life and indicators of resistance to physical exertion significantly changed in a positive direction.

Keywords: chronic heart failure, chronic kidney disease, kidney dysfunction, fibrosis markers, cystatin-S, TGF-β1, ferrokinetic markers, galectin-3, types of hemodynamics.

First page

337

Last page

343

For citation: Khalilova F.A. ASSESSMENT OF INTRACARDIAC HEMODYNAMICS AND ELECTROLYTE BALANCE IN VARIOUS HEMODYNAMIC TYPES OF CHRONIC HEART FAILURE ACCOMPANIED BY ANEMIA //New Day in Medicine 5(43)2022 337-343 https://clck.ru/p3vES

LIST OF REFERENCES:

1. Gadaev A.G., Turakulov R.I., Kurbonov A.K. Surunkali yurak yetishmovchiligida kamqonlikni uchrashi va uni kasallik kechishiga salbiy ta’siri // O‘zbekiston tibbiyot jurnali. – 2019 – 2. – S. 74 – 77.
2. Gadaev A.G, Qurbonov A.K, Sabirov M.A, Sayfullayev M.B, Gadaeva N.A., Turakulov R.I. Assessment of Erythropoietin Levels and Correlation with Cytokines in Patients with Chronic Heart Failure // International Journal of Pharmaceutical Research. – 2021. – Vol 13Р. 713-720.
3. Tosheva Kh.B., Xalilova F.A., Gadaev A.G., Erkinova N.E., Djuraeva N.O. Impact Of Chronic Heart Failure On Comorbidities In Hot Climates On The Quality Of Life And Clinical Condition Of Patients // European Journal of Molecular & Clinical Medicine. -2020 – Vol. 7, P. 1080-1089.
4. Gadaev A.G., Tosheva X.B., Elmuradov F.X., Xalilova F.A. Fibrous changes in the kidneys in patients XSN. Therapy Bulletin of Uzbekistan. 2018. – P. 86 – 90.
5. Gadaev A.G., Xalilova F.A., Elmuradov F.X., Tosheva X.B. Structural and functional changes in the kidneys and heart in patients with XSN. Therapy Bulletin of Uzbekistan. 2018. -1 – S. 100-104.
6. Gadaev A.G., Gubanov A.K., Tasheva H.B., Erkenova N.A., Turakulov R.I. Principles of treatment of chronic heart failure with anemia// Bulletin of the Tashkent Medical Academy. – 2019. -№. 2. – 18-21.
7. Tosheva Kh. B.,Gadaev A. G. Dynamics of Renal Fibrosis Markers on the Basis of Complex Treatment in Chronic Heart Failure with Anemia // Psychology and Education. – 2021.- Vol. 3.- P. 1291-1301
8. Гадаевич Г.А., Абдуджалоловна Х.Ф., Садуллаевич А.К. Оценка взаимосвязи маркеров сердечного и почечного фиброза при различных гемодинамических типах хронической сердечной недостаточности с анемией и без нее. – 2021.
9. Ашурова Н.Г., Хазифа Х.Т. The role of simulation training in the formation of professional competence of students of medical higher education institutions Academicia Globe: Inderscience Research  2 (6), (2021 г.). 303–307
10. Aslonova, I., Erkinova, N. E., & Tosheva, K. (2019). The prevalence of chronic pyelonephritis in women with disturbed tolerance for glucose. International Journal of Pharmaceutical Research, 11(4), 866-868. doi:10.31838/ijpr/2019.11.04.119