16 -5 (91) 2026 - Kurbanov O.M., Barnoyev S.Sh. - EFFECT OF TRADITIONAL THERAPY AND PENTOXIFYLLINE ON MORPHOLOGICAL AND MORPHOMETRIC CHANGES IN THE LIVER OF WHITE-BORN RATS WITH EXPERIMENTAL BURN DISEASE

EFFECT OF TRADITIONAL THERAPY AND PENTOXIFYLLINE ON MORPHOLOGICAL AND MORPHOMETRIC CHANGES IN THE LIVER OF WHITE-BORN RATS WITH EXPERIMENTAL BURN DISEASE

Kurbanov O.M. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Barnoyev S.Sh. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This study investigated morphological and morphometric changes in the liver of 3- and 9‑month‑old outbred white rats under experimental burn disease. The effects of conventional treatment, intensive therapy and pentoxifylline on liver tissue were evaluated. The results demonstrated hepatocyte vacuolization, hydropic and fatty degeneration, sinusoidal dilatation and activation of Kupffer cells. Pentoxifylline treatment improved microcirculation, reduced inflammation and preserved hepatocyte integrity. Age‑related aggravation of pathological changes and slower regenerative processes were observed.

Keywords: burn disease, liver, pentoxifylline, morphometry, hepatocyte, Kupffer cells.

First page

95

Last page

99

For citation:Kurbanov O.M., Barnoyev S.Sh. - EFFECT OF TRADITIONAL THERAPY AND PENTOXIFYLLINE ON MORPHOLOGICAL AND MORPHOMETRIC CHANGES IN THE LIVER OF WHITE-BORN RATS WITH EXPERIMENTAL BURN DISEASE//New Day in Medicine 5(91)2026 95-99 https://newdayworldmedicine.com/en/new_day_medicine/5-91-2026

List of References

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