189 -2 (88) 2026 - Umarov K.M., Ergashev N.Sh. - CLINICAL SIGNIFICANCE OF REPRODUCTIVE SYSTEM ANOMALIES IN PERSISTENT CLOACA

CLINICAL SIGNIFICANCE OF REPRODUCTIVE SYSTEM ANOMALIES IN PERSISTENT CLOACA

Umarov K.M. - National Children's Medical Center, Uzbekistan

Ergashev N.Sh. - National Children's Medical Center, Uzbekistan, Tashkent State Medical University

Resume

Aim: To study the nature and frequency of genital anomalies in patients with persistent cloaca (PC) and to determine the required extent of surgical intervention using single-stage and staged treatment approaches. Materials and Methods: Between 2021 and 2025, a comprehensive analysis of diagnostic and treatment outcomes was conducted in 39 patients with persistent cloaca who were managed at the Department of Pediatric Surgery of the National Children’s Medical Center. The frequency and patterns of genital anomalies were assessed. This pathology requires specialized diagnostic and surgical approaches. Diagnosis was based on clinical examination, instrumental and radiological studies, and specialized investigations; diagnostic laparoscopy was performed when indicated. Results: Persistent cloaca was associated with vaginal atresia, vaginal duplication, uterine and Müllerian structure duplications in 18 patients (46.1%), either as isolated anomalies or in various combinations. In cases of complete or partial genital obstruction, the development of complications and the presence of a bacterial-inflammatory component necessitated significant modifications to standard diagnostic and surgical approaches. Conclusion: Persistent cloaca in girls is often accompanied by gynecological anomalies, the type and severity of which play a crucial role in determining the surgical strategy. Timely and comprehensive diagnosis, along with individualized reconstructive surgical intervention, contributes to improved short- and long-term treatment outcomes.

Keywords: persistent cloaca, genital anomalies, diagnosis, complications, treatment.

First page

1032

Last page

1038

For citation:Umarov K.M., Ergashev N.Sh. - CLINICAL SIGNIFICANCE OF REPRODUCTIVE SYSTEM ANOMALIES IN PERSISTENT CLOACA//New Day in Medicine 2(88)2026 1032-1037 https://newdayworldmedicine.com/en/new_day_medicine/2-88-2026

List of References

  1. Адамян ЛВ, Шарков СМ, Сибирская ЕВ. Персистирующая клоака в гинекологической практике (обзор). Российский журнал детской хирургии. 2021;25(5):315–319.
  2. Киргизов ИВ, Минаев СВ, Гладкий АП. Мультицентровое исследование хирургического лечения детей с персистирующей клоакой. Медицинский вестник Северного Кавказа. 2014;9(4):295–299.
  3. Киргизов ИВ, Шишкин ИА, Апросимов МН, Апросимова СИ. Опыт хирургического лечения персистирующей клоаки у детей. Кремлёвская медицина. Клинический вестник. 2016;(3):55–58.
  4. Мокрушина ОГ, Шумихин ВС, Левицкая МВ. Результаты лечения пятидесяти детей с персистирующей клоакой в условиях одного центра. Российский вестник детской хирургии, анестезиологии и реаниматологии. 2021;11(3):315–324.
  5. Новожилов ВА, Степанова НМ, Петров ЕМ, . Опыт коррекции персистирующей клоаки у детей. Российский журнал детской хирургии, анестезиологии и интенсивной терапии. 2020;10(3 S):114.
  6. Отамурадов ФА, Эргашев НШ. Персистирующая клоака у девочек: проблемы диагностики и хирургической коррекции. Российский вестник детской хирургии, анестезиологии и реаниматологии. 2016;6(4):37–42.
  7. Отамурадов ФА, Эргашев НШ. Диагностика и результаты лечения персистирующей клоаки. Евразийский педиатрический журнал. 2019;(3):217–223.
  8. Bischoff A, AbouZeid AA, Mohammad SA, Shokry SS, El Naggar O. Posterior cloaca: a urogenital rather than anorectal anomaly. Journal of Pediatric Urology. 2021;17(3):410.e1–410.e7.
  9. Bischoff A, Levitt MA, Breech L, Hall J, Peña A, Surgical reconstruction strategies in persistent cloaca. Semin Pediatr Surg. 2016;25(2):102–107.
  10. Levitt MA, Peña A, Wang C, Li L, Cheng W, Liu S, Diao M, Li X, Guo LQ, Zhang Z, Chen Z. A new approach for persistent cloaca: laparoscopically assisted anorectoplasty and modified repair of urogenital sinus. J Pediatr Surg. 2015;50(7):1236–1240.

    file

    download