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  • 8 -8 (94) 2026 - Kazakova N.N., Xakimova Z.K., Mamatova I.Y. - TISH EMALI MINERALIZATSIYASI BILAN BOG'LIQ MOLEKULYAR BIOMARKERLARGA FTOR SAQLOVCHI DORIVOR O'SIMLIKLAR EKSTRAKTINING TA'SIRI

8 -8 (94) 2026 - Kazakova N.N., Xakimova Z.K., Mamatova I.Y. - TISH EMALI MINERALIZATSIYASI BILAN BOG'LIQ MOLEKULYAR BIOMARKERLARGA FTOR SAQLOVCHI DORIVOR O'SIMLIKLAR EKSTRAKTINING TA'SIRI

TISH EMALI MINERALIZATSIYASI BILAN BOG'LIQ MOLEKULYAR BIOMARKERLARGA FTOR SAQLOVCHI DORIVOR O'SIMLIKLAR EKSTRAKTINING TA'SIRI

Kazakova N.N., Xakimova Z.K., Mamatova I.Y. - Abu Ali ibn Sino nomidagi Buxoro davlat tibbiyot instituti

Rezyume

Maqolada ftor saqlovchi dorivor o'simliklar — Salvia officinalis L., Thymus vulgaris L., Spinacia oleracea L., Urtica dioica L. va Melissa officinalis L. asosida tayyorlangan kombinatsion suvli ekstraktning tish emali mineralizatsiyasi bilan bog'liq molekulyar biomarkerlarga (tuftelin, MMP-20, enamelin) ta'siri o'rganilgan. Tadqiqotda 40 nafar talabada o'simlik ekstrakti bilan 21 kunlik og'iz chayish kursidan oldin va keyin ELISA usulida qon zardobidagi ko'rsatkichlar taqqoslangan. Tuftelin miqdori 45,1% ga (p<0,001), MMP-20 miqdori 6,7% ga (p<0,001) statistik ishonchli o'zgargan, enamelin esa 33,8% ga oshgan (p=0,230). Umumiy qon tahlili natijalari ekstraktning gematologik xavfsizligini tasdiqladi. Olingan natijalar o'simlik ekstraktining emal mineralizatsiyasiga modulyatsiyalovchi ta'sir ko'rsatishi mumkinligini ko'rsatadi.

Kalit so'zlar: tish emali, demineralizatsiya, remineralizatsiya, tuftelin, MMP-20, enamelin, dorivor o'simliklar, ftor.

First page

60

Last page

63

For citation:Kazakova N.N., Xakimova Z.K., Mamatova I.Y. - TISH EMALI MINERALIZATSIYASI BILAN BOG'LIQ MOLEKULYAR BIOMARKERLARGA FTOR SAQLOVCHI DORIVOR O'SIMLIKLAR EKSTRAKTINING TA'SIRI//New Day in Medicine 8(94)2026 60-63 https://newdayworldmedicine.com/en/new_day_medicine/8-94-2026

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