117 -12 (50) 2022 — Isamitdinova N.Sh. — PRINCIPLES OF EARLY DETECTION OF THYROID PATHOLOGY IN PATIENTS WITH RHEUMATOID ARTHRITIS AND AUTOIMMUNE THYROIDITIS

PRINCIPLES OF EARLY DETECTION OF THYROID PATHOLOGY IN PATIENTS WITH RHEUMATOID ARTHRITIS AND AUTOIMMUNE THYROIDITIS

Isamitdinova N.Sh. Bukhara Regional Multidisciplinary Medical Center, Uzbekistan

Resume

Currently, RA is a chronic systemic inflammatory disease that affects not only the joint and peri-articular tissues, but also the central and autonomic nervous system, endocrine systems and their interrelationships, and further complicates the course of the underlying disease. Clinicians are familiar with pathologies such as goitre, hypothyroidism, adrenal gland dysfunction, which are common pathologies of endocrine glands in patients with RA. The principles of treating patients with rheumatoid arthritis and autoimmune thyroiditis are one of the complex problems of modern rheumatology. Its relevance is the progression of two autoimmune diseases (RA and AIT), the severity of damage to the musculoskeletal system, the high number of injuries among the working population, early decline in functional ability, loss of professional and social skills, difficulty in physical and psychological adaptation in patients with loss of motor function, It is defined as a general medical and social problem that causes significant economic loss, i.e. disability.

Prolongation and acceleration of the duration of the main disease leads to the development of thyroid pathology, the addition of new joints and extra-articular systems to the pathological process, the formation of irreversible, permanent changes in the joints (destruction, half-extinction, contracture). All this leads to severe functional deficiency, disruption of all aspects of life and a decrease in the quality of life of patients.

Key words: rheumatoid arthritis, autoimmune thyroiditis, thyroid gland, hyperthyroidism, hypothyroidism

First page

675

Last page

683

For citation: Isamitdinova N.Sh. – PRINCIPLES OF EARLY DETECTION OF THYROID PATHOLOGY IN PATIENTS WITH RHEUMATOID ARTHRITIS AND AUTOIMMUNE THYROIDITIS //New Day in Medicine 12(50)2022 675-683 https://clck.ru/33Gaqc

LIST OF REFERENCES:

  1. Авдеева А.С., Новиков А.А., Александрова Е.Н. и др. Связь уровней цитокинов с активностью заболевания, уровнем аутоантител и деструктивными изменениями суставов при раннем ревматоидном артрите. //Научно-практическая ревматология. 2015;53(4):385-90.
  2. Агаки С.А., Граппа Л.Г. Взаимосвязь между функцией щитовидной железы и течением ревматоидного артрита //Научно практическая ревматология. – 2001. – № 3. – С. 4
  3. Елисеева Л.В. Течение ревматоидного артрита, сочетающегося с патологией щитовидной железы: /автореф. дис. … канд. мед. наук. – Томск, 2002. – 21 с
  4. Зборовский А.Б., Фофанова Н.А. Ревматические болезни и ревматическая служба в Южном Федеральном округе: состояние и перспективы. //Научно-практическая ревматология. 2007; 3: 4-9.
  5. Зиннетуллина Н.Х. Особенности тиреоидного статуса у больных ревматоидным артритом: /автореф. дис. … канд. мед. наук. – Чебоксары, 2003. – 23 с.
  6. Ajjan R.A., Watson P.F., McIntosh R.S., Weetman A.P. Intrathyroidal cytokine gene expression in Hashimoto’s thyroiditis. //Clin Exp Immunol. 1996 Sep;105(3):523-8. doi: 10.1046/j.1365- 2249.1996.d01-784.x ;
  7. Ajjan R.A., Weetman A.P. Cytokines in thyroid autoimmunity. //Autoimmunity. 2003 SepNov;36(67):3519
  8. Al-Awadhi A.M, Olusi S., Hasan EA, Abdullah A. Frequency of abnormal thyroid function tests in Kuwaiti Arabs with autoimmune diseases. //Med Princ Pract. 2008;17(1):61-5. 
  9. Al Girgawy Sh. A.F., AlShabrawy D.A. Thyroid disorders and autoantibodies in systemic lupus erythematosus //Egypt. Rheumatol. Rehab. – 2007. – Vol. 34, No. 3. – P. 497–508
  10. Boltayev K. J. et al. Assessment of hemodynamics of the kidneys in young patients with arterial hypertension //Web of Scientist: International Scientific Research Journal. – 2022. – Т. 3. – №. 4. – С. 720-725.
  11. Boltayev K., Shajanova N. Anemia associated with polydeficiency in elderly and senile people //Galaxy International Interdisciplinary Research Journal. – 2022. – Т. 10. – №. 2. – С. 688-694.
  12. Boltayev K.J., Ruziyev Z.M., Ulug’ova Sh.T. Features changes in the hemostasis system in patients with COVID-19 //Web of Scientist: International Scientific Research Journal. – 2022. – Т. 3. – №. 5. – С. 479-486.
  13. Алиахунова М.Ю., Наимова Ш.А. Особенности поражения почек у больных ревматоидным артритом //Новый день медицины 2(30)2020 47-49 https://newdaymedicine.com/index.php/2020/07/07/10-2-30-2020
  14. Наимова Ш. А., Рузиева Ф. А. Особенности почечной коморбидности при ревматологических заболеваниях //Вестник науки и образования. – 2020. – №. 24-2 (102).
  15. Naimova N. S. et al. Features of coagulation and cellular hemostasis in rheumatoid arthritis in patients with cardiovascular pathology //Asian Journal of Multidimensional Research (AJMR). – 2019. – Т. 8. – №. 2. – С. 157-164.
  16. Наимова Ш. А., Латипова Н. С., Болтаев К. Ж. Коагуляционный и тромбоцитарный гемостаз у пациентов с ревматоидным артритом в сочетании с сердечно-сосудистом заболеваением //Инфекция, иммунитет и фармакология. – 2017. – №. 2. – С. 150-152.
  17. Sulaymanova G. T., Amonov M. K. Regional Causes of Iron Deficiency Anemia, Pathogenesis And Use Of Antianemic Drugs //The American Journal of Medical Sciences and Pharmaceutical Research (ISSN – 2689-1026) – 2021. April 30 – P. 165-170.
  18. Boltayev K.J., Naimova S.A. Risk factors of kidney damage at patients with rheumatoid arthritis //WJPR (World Journal of Pharmaceutical Research). – 2019. – Т. 8. – №. 13.
  19. Sulaymonova Gulnoza Tulkinjanovna, Raufov Alisher Anvarovich. The influence of defiency of microelements in children with bronchial hyperreactivity //ACADEMICIA: An International Multidisciplinary Research Journal (ISSN: 2249-7137) – 2020. April – Vol. 10, Issue 4, April –P. 846-853.
  20. Anvarovna N.S. Features Of Kidney Damage at Patients with Ankylosing Spondiloarthritis //Texas Journal of Medical Science. – 2021. – Т. 3. – С. 18-22.

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