47 -1 (51) 2023 — K.K. Odilov, M.A. Gofur-Okhunov, — RESULTS OF THE STUDY OF PROLIFERATIVE ACTIVITY (Ki-67) OF HIGH-QUALITY SOFT TISSUES SARCOMAS

RESULTS OF THE STUDY OF PROLIFERATIVE ACTIVITY (Ki-67) OF HIGH-QUALITY SOFT TISSUES SARCOMAS

K.K. Odilov, Bukhara Regional Branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology of the Ministry of Health of the Republic of Uzbekistan

M.A. Gofur-Okhunov, Center for the Development of Professional Qualifications of Medical Workers (TsRPKMR) of the Ministry of Health of the Republic of Uzbekistan

A.A. Madaliev, Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology “RSNPMTSOiR” of the Ministry of Health of the Republic of Uzbekistan

A.Z. Olimova Bukhara State Medical Institute

Resume

Aim of the research: The purpose of the work is to study and evaluate the most significant clinical factors of survival and distant metastasis in patients with high-grade soft tissue sarcomas.

Abstract: The article presents data on certain indicators of proliferative activity (Ki-67) in high-grade soft tissue sarcomas. Analysis of Ki-67 expression showed that in high-grade soft tissue sarcomas, Ki-67 expression in most cases depended on the histological structure of the tumor and the degree of malignancy. The rate of recurrence and metastasis was higher in synovial sarcoma and rhabdomyosarcoma compared with angiogenic sarcoma and leiomyosarcoma.

Keywords: soft tissue sarcoma, proliferative activity, histological structure, immunohistochemistry, recidivism, metastasis, survival.

First page

275

Last page

279

For citation: K.K. Odilov, M.A. Gofur-Okhunov, A.A. Madaliev, A.Z. Olimova – RESULTS OF THE STUDY OF PROLIFERATIVE ACTIVITY (Ki-67) OF HIGH-QUALITY SOFT TISSUES SARCOMAS //New Day in Medicine 1(51)2023 275-279 https://clck.ru/33S9WY

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