9 -6 (56) 2023 — Sh.A.Mustafaeva — SYSTEMIC USE OF NSAIDS IN RHEUMATOID ARTHRITIS: THE RISK OF CHRONIC KIDNEY DISEASE

SYSTEMIC USE OF NSAIDS IN RHEUMATOID ARTHRITIS: THE RISK OF CHRONIC KIDNEY DISEASE

Sh.A.Mustafaeva Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This review discusses the issues that manifest themselves in the development of pain syndrome and require the use of painkillers. One of the urgent problems of modern medicine is kidney damage in rheumatoid arthritis. Unfortunately, patients learn about most of this group of drugs from the media, and not from a doctor. The kidneys are affected in rheumatoid arthritis more often than is diagnosed. Thus, the systematic use of non-steroidal anti-inflammatory drugs (NSAIDs) can not only slow down the diagnosis of a disease accompanied by pain, but also lead to the development of other, more serious diseases. The main effects of NSAID drugs on the human body include analgesic, anti-inflammatory and antipyretic effects. These data are fully confirmed at the moment. The problem of kidney damage in rheumatoid arthritis is poorly understood and requires further study.

Key words: rheumatoid arthritis, risk factors, non-steroidal anti-inflammatory drugs, chronic kidney disease.

First page

51

Last page

56

For citation: Sh.A.Mustafaeva – SYSTEMIC USE OF NSAIDS IN RHEUMATOID ARTHRITIS: THE RISK OF CHRONIC KIDNEY DISEASE //New Day in Medicine 2023 6(56): 51-56 https://newdaymedicine.com/index.php/2023/06/09/l-93/

LIST OF REFERENCES:

  1. Akhmadovna M. S. Reasons for the Development of Morphostructural Changes in Kidney Cells in Patients with Rheumatoid Arthritis Vital Annex: International Journal of Novel Research in Advanced Sciences. (2022) 1(50:396-401.
  2. Boltayev K.J., Naimova Sh.A.  Risk factors of kidney damage at patients with rheumatoid arthritis WJPR (World Journal of Pharmaceutical Research) (2019) 8(13).
  3. Boltaeva M. M. Treatment of Arterial Hypertension in Elderly Patients and Senile Age Group.
  4. Evans JM, McGregor E, McMahon AD, et al. Non-steroidal anti-inflammatory drugs and hospitalization for acute renal failure. QJM (1995) 88:551-7.
  5. Gastropatic Comarbidity in Patients with Rheumatoid Arthritis. Djabbarova Miyassar Bobokulovna. Central asian journal of medical and natural sciences (2023) Jan-Feb 4(1):1-6.
  6. Hickson LJ, Crowson CS, Gabriel SE. Development of Reduced Kidney Function in Rheumatoid Arthritis. Am J Kidney Dis (2014) 63(2):206-213.
  7. Hickson LJ, Crowson CS, Gabriel SE. Development of Reduced Kidney Function in Rheumatoid Arthritis. Am J Kidney Dis (2014) 63(2):206-213.
  8. Hickson LJ, Crowson CS, Gabriel SE. Development of Reduced Kidney Function in Rheumatoid Arthritis. Am J Kidney Dis (2014) 63(2): 206-213
  9. Jesky M, Lambert A, Burden A. The impact of chronic kidney disease and cardiovascular comorbidity on mortality in a multiethnic population: a retrospective cohort study. BMJ Open (2013) 3(12). doi 10.1136/bmjopen-(2013)-003458
  10. Jesky M, Lambert A, Burden A. The impact of chronic kidney disease and cardiovascular comorbidity on mortality in a multiethnic population: a retrospective cohort study. BMJ Open (2013) 3(12). doi 10.1136/bmjopen-(2013)-003458
  11. Jesky M, Lambert A, Burden A. The impact of chronic kidney disease and cardiovascular comorbidity on mortality in a multiethnic population: a retrospective cohort study. BMJ Open (2013) 3(12). doi 10.1136/bmjopen-2013-003458
  12. Karie S, Gandjbakhch F, Janus N. Kidney disease in RA patients: prevalence and implication on RA-related drugs management: the MATRIX study. Rheumatology (Oxford) 2008 47(3):350- 354.
  13.  Khan KN, Paulson SK, Verburg KM, et al. Pharmacology of cyclooxygenase-2 inhibition in the kidney. Kidney Int. (2002) Apr 61(4):1210-9.
  14. Khan KN, Paulson SK, Verburg KM, et al. Pharmacology of cyclooxygenase-2 inhibition in the kidney. Kidney Int. 2002 Apr 61(4):1210-9.
  15. Kholmurodovich U.F. Damage to the digestive system when using non-steroidal anti-inflammatory drugs European journal of modern medicine and practice. (2022) 2(1):6-16.
  16.  Kholmurodovich U.F. Liver Pathology In Rheumatoid Arthritis Сentral asian journal of medical and natural sciences. (2022) 3(1):11-15.
  17. Makino H., Yoshinaga Y., Yamasaki Y, et al.  Mod. Rheumatol. (2002) 12:148-154.
  18. Moller B, Pruijm M, Adler S, Scherer A, Villiger PM, Finckh A ((2013)) Chronic NSAID use and long-term decline of renal function in a prospective rheumatoid arthritis cohort study. Ann Rheum Dis, doi: 10.1136/annrheumdis 2013-204078.
  19. Musu M. et al. Acute nephrotoxicity of NSAID from the foetus to the adult Eur. Rev. Med. Pharmacol. Sci. (2011) 15(12):1461–72.
  20. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation,classification, and stratification.  Am J Kidney Dis. (2002) 39:1-266.

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