54 -9 (59) 2023 — Sanoqulova S.A. — IMMUNO-PATHOGENETIC CHARACTERISTICS OF DEVELOPMENT OF HEPATORENAL SYNDROME IN LIVER CIRRHOSIS

IMMUNO-PATHOGENETIC CHARACTERISTICS OF DEVELOPMENT OF HEPATORENAL SYNDROME IN LIVER CIRRHOSIS

Sanoqulova S.A. Bukhara State Medical Institute named after Abu Ali ibn Sina

Rezyumе

In this article, we have collected the main data by studying the immuno-clinical mechanisms, specific features and research results of hepatorenal syndrome in cirrhosis of the liver, which is one of the urgent problems in medicine today, from the literature of Uzbekistan and the world.

Key words: hepatorenal syndrome, liver cirrhosis, innate immunity, cytokines, T-lymphocyte, CD+4 cells, antigen

First page

305

Last page

308

For citation: Sanoqulova S.A. – IMMUNO-PATHOGENETIC CHARACTERISTICS OF DEVELOPMENT OF HEPATORENAL SYNDROME IN LIVER CIRRHOSIS //New Day in Medicine 2023 9(59): 305-308 https://newdaymedicine.com/index.php/2023/10/12/l-456/

LIST OF REFERENCES:

  1. Булатова И.А., Щёкотова А.П., Долгих О.В., Падучева С.В. Цитокиновый статус у больных циррозами печени разной этиологии [Электронный ресурс//Современные проблемы науки и образования. 2016;3. URL:http://scienceeducation.ru/ru/article/view?id=24755 (дата обращения: 13.08.2020).
  2. Тонеева М..А., Куликов В.Е. Взаимосвязь между количественными параметрами печени и уровнями цитокинов у пациентов с циррозами печени вирусной этиологии //Ультразвуковая и функциональная диагностика. 2015;5:173.
  3. Albillos A., Lario M., Álvarez-Mon M. Cirrhosis-associated immune dysfunction: Distinctive features and clinical relevance. //J Hepatol., 2014;61:1385-1396.
  4. Angeli P., Merkel C. Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis. //J Hepatol., 2008;48(1):93-103.
  5. Antoniades C.G., Khamri W., Abeles R.D., Taams L.S., Triantafyllou E., Possamai L.A. et al. Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure. //Hepatology, 2014;59:1564-1576.
  6. Bajaj J.S., Heuman D.M., Hylemon P.B., Sanyal A.J., White M.B., Monteith P. et al. Altered profile of human gut microbiome is associated with cirrhosis and its complications. //J. Hepatol., 2014;60:940-947.
  7. Bauer T.M., Steinbruckner B., Brinkmann F.E., Ditzen A.K., Schwacha H., Aponte J.J. et al. Small intestinal bacterial overgrowth in patients with cirrhosis: Prevalence and relation with spontaneous bacterial peritonitis. //Am. J. Gasteroenterol., 2001;96:2962-2967.
  8. Bruewer M., Luegering A., Kucharzik T., Parkos C.A., Madara J.L., Hopkins A.M., Nusrat A. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. //J. Immunol., 2003;171:6164-6172.
  9. Busk T.M., Bendtsen F., Møller S. Hepatorenal syndrome in cirrhosis: diagnostic, pathophysiological, and therapeutic aspects. //Expert Rev. Gastroenterol. Hepatol., 2016;10(10):1153-1161.
  10. Chancharoenthana W., Leelahavanichkul A. Acute kidney injury spectrum in patients with chronic liver disease: Where do we stand?. //World J. Gastroenterol., 2019;25(28):3684-3703.
  11. Chen Y., Yang F., Lu H., Wang B., Chen Y., Lei D. et al. Characterization of fecal microbial communities in patients with liver cirrhosis. //Hepatology, 2011;54:562-572.
  12. Chiva M., Guarner C., Peralta C., Llovet T., Gomez G., Soriano G. et al. Intestinal mucosal oxidative damage and bacterial translocation in cirrhotic rats. //Eur. J. Gastroenterol. Hepatol., 2003;15:145-150.
  13. Clària J., Stauber R.E., Coenraad M.J., Moreau R., Jalan R., Pavesi M. et al. Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure. Hepatology, 2016;64:1249-1264.
  14. Colino J., Duke L., Snapper C. M. Autologous albumin enhances the humoral immune response to capsular polysaccharide covalently coattached to bacteria-sized latex beads. //European Journal of Immunology, 2014;44(5):1433-1443.
  15. Dagher L., Moore K. The hepatorenal syndrome. Gut., 2001;49(5):729-737.
  16. Арипходжаева Г., Арипходжаева Ф., Гепато-Ренальный Синдром При Хроническом Вирусном Гепатите С Евразийский Союз Ученых (ЕСУ) 2016;5(26):12-13.
  17. Бурневич Э.З., Наместников Е.В., Лопаткина Т.Н. Гепаторенальный синдром. Обзор литературы //Тер. Арх. 2002;6:76-80.
  18. Игнатова Т.М., Апросина З.Г., Серов В.В., Мухин Н.А., Крель П.Е., Козловская Л.В. Внепеченочные проявления хронической HCV-инфекции // Российский медицинский журнал. 2001;2:13-18.
  19. Крутиков Е.С., Вострикова А.Н., Крутикова М.С. Гепаторенальный cиндром: современные представления о патогенезе (часть 1). //Южно-Российский журнал терапевтической практики. 2021;2(4):16-21.
  20. Mukhammadieva M.I. (2022). Modern Clinical and Biochemical Characteristics of Liver Cirrhosis Patients of Viral Etiology with Spontaneous Bacterial Peritonitis //Texas Journal of Medical Science. 2022;86-90.

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