34 -2 (34) 2021 — Yuldasheva R.U., Zharylkasynova G.Zh. — THE EFFECTIVENESS OF THERAPY FOR IRON DEFICIENCY ANEMIA IN PATIENTS INFECTED WITH HELICOBACTER PYLORI

THE EFFECTIVENESS OF THERAPY FOR IRON DEFICIENCY ANEMIA IN PATIENTS INFECTED WITH HELICOBACTER PYLORI

Yuldasheva R.U., Bukhara State Medical Institute

Zharylkasynova G.Zh. Bukhara State Medical Institute

Resume

Purpose. To study the dynamics of clinical and laboratory parameters in patients with IDA infected with H. pylori. Material and methods. The study included 60 patients with IDA infected with H. pylori. Depending on the therapy, the patients were randomly divided into 2 homogeneous groups: the main group received therapy with iron preparations along with eradication therapy; the control group included patients receiving therapy only with iron preparations for 1 month. Evaluation of the effectiveness of IDA therapy was carried out on the basis of monitoring indicators of hemoglobin (Hb), color index (CP) and ferritin. Results. The period of taking iron-containing drugs was accompanied by a significant (p <0.05) increase in Hb and CP levels. By the 28th day of treatment, all patients reached the target values ​​corresponding to mild IDA. At the same time, among the patients of the main group, the target indicators were achieved by the majority of patients by the 22-25th day of therapy (p <0.05). A significant increase in the level of ferritin was also noted, which indicates an earlier onset of its deposition in the body (p <0.05). Moreover, among patients who underwent a preliminary course of antibiotic therapy, these indicators were higher. Conclusion. Eradication therapy in individuals infected with H. pylori and suffering from chronic IDA allows a faster response to treatment with oral iron preparations.

Key words: iron deficiency anemia; Helicobacter pylori; iron preparations; eradication therapy.

First page

173

Last page

177

For citation: Yuldasheva R.U., Zharylkasynova G.Zh. The effectiveness of therapy for iron deficiency anemia in patients infected with helicobacter pylori //New Day in Medicine 2(34)2021 173-177 https://cutt.ly/BnoJ6Ts

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