6 -1 (25/1) 2019 — Jurayeva G.B., Saidova L.A., — CORRELATION INTERRELATION BETWEEN CLINIC-LABORATOR INDICATORS AND STRUCTURAL CHANGES IN KIDNEYS AT EACH MORPHOLOGICAL FORM OF CHRONIC GLOMERULONEFRIT WHICH IS FOLLOWED NEPHROTIC BY THE SYNDROME

CORRELATION INTERRELATION BETWEEN CLINIC-LABORATOR INDICATORS AND STRUCTURAL CHANGES IN KIDNEYS AT EACH MORPHOLOGICAL FORM OF CHRONIC GLOMERULONEFRIT WHICH IS FOLLOWED NEPHROTIC BY THE SYNDROME

Jurayeva G.B., Bukhara state medical institute.

Saidova L.A., Bukhara state medical institute.

Ramazonova Sh.Sh. Bukhara state medical institute.

Resume,

Results of 104 biopsies received from patients with a nephrotic syndrome are studied. Material for research was built a current of 2006-2010. Comprehensive clinic-laboratory examination is conducted at 78 patients. From them at 58 the proteinuric form of a chronic glomerulonephritis is established. Average age of patients made 24, 9+5, 2 years. Depending on morphological option of a glomerulonephritis, all patients were distributed on 6 groups. Data correlation the analysis of the studied morphometric parametric and data of routine laboratory researches I allowed to create mathematical model by which it is possible to define a morphological form of a chronic glomerulonephritis. At impossibility carrying out a biopsy of kidneys for definition of a morphological form of the chronic glomerulonephritis proceeding with nephrotic a syndrome doctors to nephrologists are recommended to use the developed mathematical model.

Keywords. Chronic glomerulonephritis, a nephrotic syndrome, a biopsy

First page

27

Last page

29

For citation: Jurayeva G.B., Saidova L.A., Ramazonova Sh.Sh. Correlation interrelation between clinic-laborator indicators and structural changes in kidneys at each morphological form of chronic glomerulonefrit which is followed nephrotic by the syndrome//New Day in Medicine 1(25)2019 27-29 https://cutt.ly/0bDVuH8

List of References

1. Абрамова Т.В. Нейтрофилы при гломерулонефрите /Т.В. Абра­мова //Нефрология. – 2005. – №9(2) – С. 9-16.
2. Баринов Э.Ф. Метаболиты арахидоновой кислоты детерминан­ты паренхиматозно-стромальных отношений в почках в норме и при патологии / Э.Ф. Баринов, О.Н. Сулаева, М.М. Лаш // Нефрология. – 2006. – №3. – С. 14-22.
3. Батракова И.В. Цитостатическая терапия нефротического син­дрома с минимальными изменениями у детей и подростков / И.В. Батракова, Н.Д. Савенкова // Нефрология. – 2004. – №2. – С. 98-105.
4. Игнатова М.С. Проблема прогрессирования болезней почек у детей и современные возможности ренопротекции / М.С. Иг­натова // Нефрология и диализ. – 2005. – №4. – С. 428-434.
5. Buf-Vereijken P.W.C. Efficacy of a second course of immuno­suppressive therapy in patients with membranouse nephropathy and persistent or relapsing disease activity / P.W.C. Buf-Vereijken, J.F.M. Wetzels // Nephrol. Dial. Transplant. – 2004. – №19 – P. 2036-2043.
6. Barletta G.M. Use of mycophenolate mofetil in steroid-dependent and resistant nephrotic syndrome / G.M. Barletta, W.E. Smoyer, T.E. Bunchman et al. //Pediatr. Nephrol. – 2003; – с. 18, 833-837.